Recombinant Human LONP1 cell lysate

• Cat.No.: LONP1-1423HCL

Specification

• Description: This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: LONP1 lon peptidase 1, mitochondrial [ Homo sapiens ]
• Official Symbol: LONP1
• Synonyms: LONP1; lon peptidase 1, mitochondrial; protease, serine, 15 , PRSS15; lon protease homolog, mitochondrial; hLON; LonHS; PIM1; serine protease 15; protease, serine, 15; Lon protease-like protein; hLON ATP-dependent protease; mitochondrial lon peptidase 1; mitochondrial lon protease-like protein; mitochondrial ATP-dependent protease Lon; LON; LONP; PRSS15; MGC1498
• Gene ID: 9361
• mRNA Refseq: NM_004793
• Protein Refseq: NP_004784
• MIM: 605490
• UniProt ID: P36776
• Chromosome Location: 19p13.2
• Function: ADP binding; ATP binding; ATP-dependent peptidase activity; ATPase activity; DNA polymerase binding; G-quadruplex DNA binding; mitochondrial heavy strand promoter anti-sense binding; NOT mitochondrial heavy strand promoter sense binding; mitochondrial light strand promoter anti-sense binding; NOT mitochondrial light strand promoter sense binding; nucleotide binding; peptidase activity; protein binding; sequence-specific DNA binding; serine-type endopeptidase activity; single-stranded DNA binding; single-stranded RNA binding