"PTPN18" Related Products

Recombinant Human PTPN18 cell lysate

Cat.No.: PTPN18-1437HCL
Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) [ Homo sapiens ]
Official Symbol: PTPN18
Synonyms: BDP1; PTP-HSCF
Gene ID: 26469
mRNA Refseq: NM_014369.3
Protein Refseq: NP_055184.2
MIM: 606587
UniProt ID: Q99952
Chromosome Location: 2q21.1
Pathway: B Cell Receptor Signaling Pathway, organism-specific biosystem;
Function: non-membrane spanning protein tyrosine phosphatase activity;

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