Recombinant Human RASA3 cell lysate

• Cat.No.: RASA3-1474HCL

Specification

• Description: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: RASA3 RAS p21 protein activator 3 [ Homo sapiens ]
• Official Symbol: RASA3
• Synonyms: RASA3; RAS p21 protein activator 3; ras GTPase-activating protein 3; GAP1IP4BP; GAPIII; GAP1(IP4BP); ins P4-binding protein; GTPase activating protein III; Ins(1,3,4,5)P4-binding protein; inositol 1,3,4,5-tetrakisphosphate-binding protein; MGC46517; MGC47588
• Gene ID: 22821
• mRNA Refseq: NM_007368
• Protein Refseq: NP_031394
• MIM: 605182
• UniProt ID: Q14644
• Chromosome Location: 13q34
• Pathway: MAPK Cascade, organism-specific biosystem
• Function: GTPase activator activity; Ras GTPase activator activity; calcium-release channel activity; metal ion binding