"RGS14" Related Products

Recombinant Human RGS14 cell lysate

Cat.No.: RGS14-1502HCL
Description: This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: RGS14 regulator of G-protein signaling 14 [ Homo sapiens ]
Official Symbol: RGS14
Synonyms: RGS14; regulator of G-protein signaling 14; regulator of G protein signalling 14; regulator of G-protein signalling 14;
Gene ID: 10636
mRNA Refseq: NM_006480
Protein Refseq: NP_006471
MIM: 602513
UniProt ID: O43566
Chromosome Location: 5q35.3
Pathway: Calcium Regulation in the Cardiac Cell, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem;
Function: GDP-dissociation inhibitor activity; GTPase activating protein binding; GTPase activator activity; GTPase activator activity; microtubule binding; protein kinase binding; receptor signaling complex scaffold activity; receptor signaling protein activity;

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