Recombinant Human RGS14 cell lysate
Cat.No. : | RGS14-1502HCL |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | RGS14 regulator of G-protein signaling 14 [ Homo sapiens ] |
Official Symbol : | RGS14 |
Synonyms : | RGS14; regulator of G-protein signaling 14; regulator of G protein signalling 14; regulator of G-protein signalling 14; |
Gene ID : | 10636 |
mRNA Refseq : | NM_006480 |
Protein Refseq : | NP_006471 |
MIM : | 602513 |
UniProt ID : | O43566 |
Chromosome Location : | 5q35.3 |
Pathway : | Calcium Regulation in the Cardiac Cell, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem; |
Function : | GDP-dissociation inhibitor activity; GTPase activating protein binding; GTPase activator activity; GTPase activator activity; microtubule binding; protein kinase binding; receptor signaling complex scaffold activity; receptor signaling protein activity; |
Products Types
◆ Recombinant Protein | ||
RGS14-1007H | Recombinant Human RGS14 Protein (P2-L566), Tag Free | +Inquiry |
RGS14-4674R | Recombinant Rat RGS14 Protein, His (Fc)-Avi-tagged | +Inquiry |
Rgs14-5493M | Recombinant Mouse Rgs14 Protein, Myc/DDK-tagged | +Inquiry |
RGS14-1008H | Recombinant Human RGS14 Protein (P2-L566), His tagged | +Inquiry |
RGS14-7564M | Recombinant Mouse RGS14 Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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