"TYR" Related Products


Recombinant Human TYR cell lysate

Cat.No.: TYR-1869HCL
Description: The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3 half of this gene.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: TYR tyrosinase (oculocutaneous albinism IA) [ Homo sapiens ]
Official Symbol: TYR
Synonyms: TYR; tyrosinase (oculocutaneous albinism IA); tyrosinase; OCAIA; LB24-AB; SK29-AB; monophenol monooxygenase; tumor rejection antigen AB; CMM8; OCA1A; SHEP3;
Gene ID: 7299
mRNA Refseq: NM_000372
Protein Refseq: NP_000363
MIM: 606933
UniProt ID: P14679
Chromosome Location: 11q14-q21
Pathway: Catecholamine biosynthesis, tyrosine =>dopamine => noradrenaline => adrenaline, organism-specific biosystem; Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline =>
Function: copper ion binding; metal ion binding; monooxygenase activity; monophenol monooxygenase activity; protein binding; protein heterodimerization activity; protein homodimerization activity;

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