Recombinant Human XRN1 cell lysate

• Cat.No.: XRN1-1940HCL

Specification

• Description: SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: XRN1 5-3 exoribonuclease 1 [ Homo sapiens ]
• Official Symbol: XRN1
• Synonyms: XRN1; 5-3 exoribonuclease 1; SEP1; strand-exchange protein 1 homolog; FLJ41903; DKFZp434P0721; DKFZp686B22225; DKFZp686F19113
• Gene ID: 54464
• mRNA Refseq: NM_001042604
• Protein Refseq: NP_001036069
• MIM: 607994
• UniProt ID: Q8IZH2
• Chromosome Location: 3q23
• Pathway: Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Gene Expression, organism-specific biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem; Regulation of mRNA Stability by Proteins that Bind AU-rich Elements, organism-specific biosystem
• Function: 5-3 exonuclease activity; DNA binding; RNA binding; hydrolase activity; protein binding