"XRN1" Related Products


Recombinant Human XRN1 cell lysate

Cat.No.: XRN1-1940HCL
Description: SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: XRN1 5-3 exoribonuclease 1 [ Homo sapiens ]
Official Symbol: XRN1
Synonyms: XRN1; 5-3 exoribonuclease 1; SEP1; strand-exchange protein 1 homolog; FLJ41903; DKFZp434P0721; DKFZp686B22225; DKFZp686F19113;
Gene ID: 54464
mRNA Refseq: NM_001042604
Protein Refseq: NP_001036069
MIM: 607994
UniProt ID: Q8IZH2
Chromosome Location: 3q23
Pathway: Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Gene Expression, organism-specific biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem; Regulation of mRNA Stability by Proteins that Bind AU-rich Elements, organism-specific biosystem;
Function: 5-3 exonuclease activity; DNA binding; RNA binding; hydrolase activity; protein binding;

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