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Recombinant Human H1F0 cell lysate

Cat.No. : H1F0-2117HCL
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  • Gene Information
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Description : Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : H1F0 H1 histone family, member 0 [ Homo sapiens ]
Official Symbol : H1F0
Synonyms : H1F0; H1 histone family, member 0; H1FV; histone H1.0; H1.0; H1(0); H1 0; H10; histone H1; histone H1(0); H1.0, H1(0), H1-0; MGC5241;
Gene ID : 3005
mRNA Refseq : NM_005318
Protein Refseq : NP_005309
MIM : 142708
UniProt ID : P07305
Chromosome Location : 22q13.1
Pathway : Activation of DNA fragmentation factor, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis induced DNA fragmentation, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem;
Function : DNA binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is there a relationship between the expression level of H1F0 and the disease? 05/04/2022

Studies have shown that the expression level of H1F0 is associated with a variety of diseases. For example, in some cancers, the expression level of H1F0 is upregulated, which promotes the proliferation and metastasis of tumor cells. In some neurodegenerative diseases, the expression of H1F0 may be down-regulated, leading to cell death.

What is the relationship of H1F0 to other genes or proteins? 10/06/2021

H1F0 has a complex relationship with other genes or proteins. For example, it interacts with some transcription factors and regulatory proteins of signal transduction pathways, affecting gene expression and cell signal transduction. In addition, H1F0 is also affected by some epigenetic modifications, such as methylation and acetylation.

How can we better understand the role of H1F0 in disease? 03/26/2021

In order to better understand the role of H1F0 in diseases, further in-depth research is needed on its specific mechanism of action and function. In addition, it is also necessary to study the changes in its expression level and activity in different diseases, as well as its relationship with the occurrence and development of diseases. At the same time, it is also necessary to explore the clinical application prospects and effects of the therapeutic strategies that regulate them.

What is the location and role of H1F0 in cells? 05/12/2020

H1F0 is mainly located in the nucleus, binds to chromatin (DNA-protein complex) and regulates its structure. It is able to influence the way DNA is folded and packaged, which in turn affects gene expression and DNA repair. In addition, H1F0 is also involved in the regulation of cell division and cell cycle.

What are the limitations of research on H1F0? 02/24/2020

There are still some limitations in the current research on H1F0, such as the lack of in-depth research on its specific mechanism and function, and the incomplete understanding of its relationship with diseases. In addition, since H1F0 is a multifunctional protein, regulating it may also have some side effects.

Is there a treatment strategy for H1F0? 12/02/2019

Therapeutic strategies for H1F0 include inhibiting its expression, modulating its activity, or using gene therapy. For example, some studies have shown that the use of small molecule inhibitors targeting H1F0 can inhibit its activity and thus treat some H1F0-related diseases. In addition, related diseases can also be treated by regulating the expression level of H1F0.

Customer Reviews (3)

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Reviews
09/13/2023

    H1F0 has good stability and long-term storage without problems.

    06/08/2023

      Strong stability, can form a stable micelle structure.

      11/18/2021

        It performs well in western blotting experiments.

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