Recombinant Human PDE8B, GST-tagged

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human PDE8B, GST-tagged

Recombinant Human PDE8B, GST-tagged

PDE8B Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : PDE8B-1614H
Product Overview : Recombinant human PDE8B (113-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
Source : Sf9 insect cells
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 40 nmol/min/mg
Molecular Mass : ~115 kDa
Protein length : 113-end
Purity : >85%
Applications : PDE Assay
Stability : 1 yr at -70oC from date of shipment.
Storage : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 ug/ul
Gene Name : PDE8B phosphodiesterase 8B [ Homo sapiens ]
Official Symbol : PDE8B
Synonyms : PDE8B; phosphodiesterase 8B; high affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8B
Gene ID : 8622
mRNA Refseq : NM_003719
Protein Refseq : NP_003710
MIM : 603390
UniProt ID : O95263
Chromosome Location : 5q13.3
Pathway : G Protein Signaling Pathways; GPCR downstream signaling; Purine metabolism
Function : 3',5'-cyclic-AMP phosphodiesterase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity; metal ion binding

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Verification Code Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy