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Recombinant Human Progesterone receptor LBD/Hsp90 complex, GST-tagged

Cat.No. : PGR-106H
Product Overview : Recombinant Human GST-tagged Progesterone receptor ligand-binding domain (PR-LBD) consists of a 218 a.a. GST tag, a 31 a.a. flexible linker and a 305 a.a. PR-LBD, Acc# NP_000917, amino acids 630-933. A complex of human PR-LBD with human Hsp90 (PR-LBD/Hsp90) was produced in insect cells co-infected with two recombinant baculoviruses. GST tagged PR-LBD and Hsp90 are the major components of the complex.
Source : Sf9 insect cells
Species : Human
Tag : GST
Form : 20 mM Na-P pH 8.0, 40 mM KCl, 20 mM Na2MoO4, 5 mM DTT, 7 mM reduced glutathione, 15% glycerol.
Purity : >80%
Applications : Ligand binding and coactivator peptide recruitment assays.
Storage : Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.
Gene Name : PGR progesterone receptor [ Homo sapiens ]
Official Symbol : PGR
Synonyms : PGR; progesterone receptor; NR3C3; PR; nuclear receptor subfamily 3 group C member 3;
Gene ID : 5241
mRNA Refseq : NM_000926
Protein Refseq : NP_000917
MIM : 607311
UniProt ID : P06401
Chromosome Location : 11q22-q23
Pathway : Cellular roles of Anthrax toxin, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem; Oocyte meiosis, organism-specific biosystem;
Function : DNA binding; enzyme binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; receptor activity; receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; zinc ion binding;

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