"IKBKE" Related Products


Recombinant Human IKBKE, GST-tagged

Cat.No.: IKBKE-125H
Product Overview: Full length recombinant human IKK epsilon was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines.
Source: Sf9 insect cells using baculovirus
Species: Human
Tag: GST
Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity: 12 nmol/min/mg
Molecular Mass: 110 kDa
Purity: >70%
Applications: Kinase Assay; Western Blot
Stability: 1 yr at -70°C from date of shipment.
Storage: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration: 0.05 ug/ul
Gene Name: IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon [ Homo sapiens (human) ]
Official Symbol: IKBKE
Synonyms: IKBKE; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; inhibitor of nuclear factor kappa-B kinase subunit epsilon; IKK i; IKKE; KIAA0151; IKK-epsilon; I-kappa-B kinase epsilon; inducible IkappaB kinase; IKK-related kinase epsilon; inducible I kappa-B kinase; IKKI; IKK-E; IKK-i; MGC125294; MGC125295; MGC125297
Gene ID: 9641
mRNA Refseq: NM_014002
Protein Refseq: NP_054721
MIM: 605048
UniProt ID: Q14164
Chromosome Location: 1q32.1
Pathway: Activated TLR4 signalling; Cytosolic DNA-sensing pathway; Herpes simplex infection
Function: ATP binding; IkappaB kinase activity; NF-kappaB-inducing kinase activity; protein binding

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