Native Mouse Apotransferrin


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Native Mouse Apotransferrin

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Cat.No. : Trf-70M
Description : Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and in prevention of iron loss via the kidney. Stored in bone marrow as TF-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypo-proteinemias and nephritic syndrome; increases are found in pregnancy, iron-deficiency anemias and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important factor used in defined culture media.
Source : Mouse Plasma
Species : Mouse
Form : Lyophilized
Molecular Mass : 80.0 kDa
Purity : Purity by SDS-PAGE: ≥98%
Usage : For Research Use Only! Not For Use in Humans.
Notes : Centrifuge the vial prior to opening
Storage : -20°C
Storage Buffer : Lyophilized from 20 mM Na phosphate, pH 7.4 and 150 mM NaCI.
Shipping : Gel pack
Gene Name : Trf transferrin [ Mus musculus ]
Official Symbol : Trf
Synonyms : HP; Tf; Tfn; hpx; Cd176; AI266983; serotransferrin; siderophilinbeta-1 metal-binding globulin; hypotransferrinemia with hemochromatosis
Gene ID : 22041
mRNA Refseq : NM_133977
Protein Refseq : NP_598738
UniProt ID : Q921I1
Chromosome Location : 9 F1-F3; 9 55.03 cM
Pathway : HIF-1 signaling pathway, organism-specific biosystem; Iron Homeostasis, organism-specific biosystem; Mineral absorption, organism-specific biosystem
Function : ferric iron binding; ferric iron transmembrane transporter activity; metal ion binding; metal ion binding; protein binding

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