Native Bovine Calmodulin
Cat.No. : | CALM3-74B |
- Specification
- Gene Information
- Related Products
Description : | Calmodulin (CaM) is a ubiquitous, calcium-binding protein that can bind to and regulate a multitude of different protein targets, thereby affecting many different cellular functions. CaM mediates processes such as inflammation, metabolism, apoptosis, muscle contraction, intracellular movement, short-term and long-term memory, nerve growth and the immune response. CaM is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes. Many of the proteins that CaM binds are unable to bind calcium themselves, and as such use CaM as a calcium sensor and signal transducer. CaM can also make use of the calcium stores in the endoplasmic reticulum, and the sarcoplasmic reticulum. CaM undergoes a conformational change upon binding to calcium, which enables it to bind to specific proteins for a specific response. CaM can bind up to four calcium ions, and can undergo post-translational modifications, such as phosphorylation, acetylation, methylation and proteolytic cleavage, each of which can potentially modulate its actions. |
Source : | Bovine Brain |
Species : | Bovine |
Form : | Lyophilized |
Molecular Mass : | 16 kDa |
Purity : | Purity by SDS-PAGE: ≥95% |
Usage : | For Research Use Only! Not For Use in Humans. |
Notes : | Centrifuge the vial prior to opening |
Storage : | -20°C |
Storage Buffer : | Lyophilized in 30 mM Hepes, pH 7.4, 1 mM CaCl2 and 0.1 mM DTT. |
Reconstitution : | In water or aqueous buffer |
Shipping : | Gel pack |
Gene Name : | CALM3 calmodulin 3 (phosphorylase kinase, delta) [ Bos taurus ] |
Official Symbol : | CALM3 |
Synonyms : | calmodulin |
Gene ID : | 520277 |
mRNA Refseq : | NM_001046249 |
Protein Refseq : | NP_001039714 |
UniProt ID : | P62157 |
Chromosome Location : | chromosome: 18 |
Pathway : | Activation of Ca-permeable Kainate Receptor, organism-specific biosystem; Activation of Kainate Receptors upon glutamate binding, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem |
Products Types
◆ Recombinant Protein | ||
CALM3-759R | Recombinant Rat CALM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CALM3-2291H | Recombinant Human CALM3 Protein, MYC/DDK-tagged | +Inquiry |
CALM3-1191M | Recombinant Mouse CALM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Calm3-747M | Recombinant Mouse Calm3 Protein, MYC/DDK-tagged | +Inquiry |
CALM3-093H | Recombinant Human CALM3 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
CALM3-7888HCL | Recombinant Human CALM3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCALM3 is essential for regulating calcium levels in cardiac muscle cells. It binds to calcium and activates various proteins that control muscle contraction, ensuring proper heart function.
CALM3 interacts with a range of target proteins and enzymes, influencing processes like muscle contraction and cellular responses to calcium.
Targeting CALM3 may hold therapeutic potential for managing conditions where calcium regulation is disrupted, offering new avenues for treatment and intervention.
CALM3 can interact with transcription factors and enzymes to influence gene expression. This is critical for calcium-dependent processes such as muscle development and neural function.
CALM3 is involved in calcium-dependent signaling pathways, regulating processes like muscle contraction, enzyme activation, and gene expression.
Customer Reviews (3)
Write a reviewThe product is a reliable partner in my research journey.
This product is a game-changer in terms of laboratory materials.
I've never had any issues with the product; it's a fantastic investment.
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