Native Human Catalase

• Cat.No.: CAT-75H

Specification

• Description: Composed of four identical subunits each with a molecular weight of 59,700. Catalyzes the reaction 2H?O? to H?O+O?. Catalase, along with the superoxides dismutase and glutathione peroxidase, controls the levels of oxygen-derived free radicals in mammalian cells, and together may function as a somatic oxidant defense.
• Source: Human Erythrocyte
• Species: Human
• Form: Liquid
• Molecular Mass: 244.0 kDa
• Purity: Purity by SDS-PAGE: ≥95%
• Usage: For Research Use Only! Not For Use in Humans.
• Notes: Centrifuge the vial prior to opening
• Storage: -70°C
• Storage Buffer: Frozen in 50 mM Tris-HCl, pH 8.0
• Shipping: Dry Ice

Gene Information

• Gene Name: CAT catalase [ Homo sapiens ]
• Official Symbol: CAT
• Synonyms: CAT; catalase; MGC138422; MGC138424
• Gene ID: 847
• mRNA Refseq: NM_001752
• Protein Refseq: NP_001743
• MIM: 115500
• UniProt ID: P04040
• Chromosome Location: 11p13
• Pathway: Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Folate Metabolism, organism-specific biosystem; FoxO family signaling, organism-specific biosystem; Glyoxylate and dicarboxylate metabolism, organism-specific biosystem; Glyoxylate and dicarboxylate metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem
• Function: NADP binding; aminoacylase activity; catalase activity; catalase activity; heme binding; metal ion binding; oxidoreductase activity, acting on peroxide as acceptor; protein homodimerization activity