Native Human Haptoglobin
Cat.No. : | HP-200H |
- Specification
- Gene Information
- Related Products
Description : | An acute-phase plasma protein found in human plasma at 100-300 mg per 100 ml. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes: Hp 1-1, Hp 2-1, and Hp 2-2. While the phenotypic distribution can vary greatly between ethnicities and geographic location, the Hp 2-1 phenotype is the most prevalent phenotype in humans. Plasma concentrations of haptoglobin are highest in individuals with Hp 1-1, intermediate in Hp 2-1 individuals, and lowest in Hp 2-2 individuals. Hp 1-1 is the most effective at binding hemoglobin, and Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype. |
Source : | Human Plasma |
Species : | Human |
Form : | Lyophilized |
Molecular Mass : | MW: Hp 1-1: 86,000; Hp 2-1: 200,000; Hp 2-2: 400,000 |
Purity : | >=95% by SDS-PAGE |
Usage : | For research use only |
Quality Control Test : | Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. |
Stability : | >1 year |
Storage : | -20°C |
Storage Buffer : | Salt-free lyophilized solid. Packaged and sold in 1 mg aliquots. |
Gene Name : | HP haptoglobin [ Homo sapiens ] |
Official Symbol : | HP |
Synonyms : | HP; haptoglobin; zonulin; binding peptide; haptoglobin alpha(1S)-beta; haptoglobin alpha(2FS)-beta; haptoglobin, beta polypeptide; haptoglobin, alpha polypeptide; BP; HPA1S; HP2ALPHA2; MGC111141; |
Gene ID : | 3240 |
mRNA Refseq : | NM_001126102 |
Protein Refseq : | NP_001119574 |
MIM : | 140100 |
UniProt ID : | P00738 |
Chromosome Location : | 16q22.2 |
Pathway : | amb2 Integrin signaling, organism-specific biosystem; |
Function : | catalytic activity; hemoglobin binding; serine-type endopeptidase activity; |
Products Types
◆ Recombinant Protein | ||
Hp-1162M | Recombinant Mouse Hp Protein, MYC/DDK-tagged | +Inquiry |
HP-5001H | Recombinant Human HP Protein, GST-tagged | +Inquiry |
HP-079H | Recombinant Human HP Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
HP-1891H | Recombinant Human HP Protein, MYC/DDK-tagged | +Inquiry |
HP-1955R | Recombinant Rhesus Macaque HP Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
HP-75C | Native Canine Haptoglobin | +Inquiry |
HP-127H | Native Human Hemoglobin protein | +Inquiry |
Hp-25 | Native Helicobacter pylori Antigen | +Inquiry |
◆ Lysates | ||
HP-5408HCL | Recombinant Human HP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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