Native Rat Transferrin

• Cat.No.: Tf-264R

Specification

• Description: Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and in prevention of iron loss via the kidney. Stored in bone marrow as TF-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypo-proteinemias and nephritic syndrome; increases are found in pregnancy, iron-deficiency anemias and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important factor used in defined culture media.
• Source: rat plasma
• Species: Rat
• Form: Lyophilized
• Molecular Mass: MW: 80,000 by SDS PAGE
• Purity: >= 98% by SDS-PAGE
• Usage: For research or further manufacturing use only.
• Stability: 1 year
• Storage: -20°C
• Storage Buffer: 20 mM Na phosphate, pH 7.4, 150 mM NaCI

Gene Information

• Gene Name: Tf transferrin [ Rattus norvegicus ]
• Official Symbol: Tf
• Synonyms: TF; transferrin; serotransferrin; siderophilin; beta-1 metal-binding globulin; liver regeneration-related protein LRRG03; Tfn; Trf; MGC93500
• Gene ID: 24825
• mRNA Refseq: NM_001013110
• Protein Refseq: NP_001013128
• Pathway: Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem
• Function: ferric iron binding; ferric iron transmembrane transporter activity; metal ion binding