Cat. No. :	Adipoq-75M
Product Overview :	Recombinant mouse globular domain of adiponectin/acrp30 (amino acid residues, 111-247, gAcrp30) was overexpressed in E.coli and purified by using conventional chromatography techniques, 16 kDa (138 aa).
Description :	Adiponectin/Acrp30 (247amino acids) is adipocyte complement-related protein of 30kDa and exclusively expressed in differentiated adipocytes. Adiponectin (Acrp30) is a member of the complement factor C1q family and consists of signal sequence, Non-homologous sequence, collagen domain and globular domain (gAcrp30). Adiponectin (Acrp30) expression is reduced in a variety of obese and insulin-resistant states in human, monkeys and mice. Injection of Acrp30 (247aa) or gAcrp30 (globular domain) lowers serum glucose and free fatty acid level in mice.
Sequences of amino acids :	MAYMYRSAFS VGLETRVTVP NVPIRFTKIF YNQQNHYDGS TGKFYCNIPG LYYFSYHITV YMKDVKVSLF KKDKAVLFTY DQYQEKNVDQ ASGSVLLHLE VGDQVWLQVY GDGDHNGLYA DNVNDSTFTG FLLYHDTN
Formulation :	Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 50 mM NaCl, 5 mM DTT, 10% glycerol
Purity :	> 95% by SDS - PAGE
Concentration :	1 mg/ml (determined by Bradford assay)
Storage :	Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Name :	Adipoq adiponectin, C1Q and collagen domain containing [ Mus musculus ]
Synonyms :	ACDC; ACRP30 ; ADIPQTL1; ADPN ; APM-1; APM1; AdipoQ;GBP28; adiponectin; apM-1; apM1; 30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; Adipocyte, C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; Gelatin-binding protein; adipocyte, C1Q and collagen domain containing; adipocyte, C1Q and collagen domain-containing; adiponectin, C1Q and collagen domain containing; adipose most abundant gene transcript 1; gelatin-binding protein 28; APN; 30kDa; adipo; adipocyte complement related protein; gAcrp30
Gene ID :	11450
mRNA Refseq :	NM_009605
Protein Refseq :	NP_033735
MIM :
UniProt ID :	Q60994
Chromosome Location :	16 16.0 cM
Pathway :	Adipocytokine signaling pathway; PPAR signaling pathway; Type II diabetes mellitus
Function :	hormone activity; protein binding; receptor binding

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