"CPLX1" Related Products

Expand
Expand

Recombinant Human Complexin 1, His-tagged

Cat. No.: CPLX1-305H
Product Overview: Recombinant Complexin 1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (154 aa, 17.1 kDa).
Description: Complexin1 belongs to a family of SNARE complex binding proteins that were suggested to be either facilitators or inhibitors of vesicle exocytosis. Complexin 1 exhibits reduced Ca2+-triggered fast neurotransmitter release at hippocampal glutamatergic synapses, indicating that this protein is a positive regulator of transmitter release. In contrast, it inhibits SNARE-mediated liposome and cell fusions in vitro, which lead to the hypothesis that it acts as fusion clamps of synaptic exocytosis.
Source: E.coli.
Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
Molecular Weight: 17.1 kDa (154 aa) (Real molecular weight on SDS-PAGE will be shift up).
Purity: > 90% by SDS – PAGE.
Concentration: 1 mg/ml (determined by Bradford assay).
Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method).
Sequence: MGSSHHHHHH SSGLVPRGSH MEFVMKQALG GATKDMGKML GGDEEKDPDA AKKEEERQEA LRQAEEERKA KYAKMEAERE AVRQGIRDKY GIKKKEEREA EAQAAMEANS EGSLTRPKKA IPPGCGDEVE EEDESILDTV IKYLPGPLQD MLKK
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: CPLX1
Synonyms: CPLX1; complexin 1; CPX1; CPX-I; CPLX1; CPX I; Complexin I; complexin 1 synaphin 2; Synaphin-2.
Gene ID: 10815
mRNA Refseq: NM_006651.3
Protein Refseq: NP_006642.1
MIM: 605032
UniProt ID: O14810
Chromosome Location: 4p16.3
Pathway: Synaptic Transmission.
Function: syntaxin binding.

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.