Recombinant Human Complexin 1, His-tagged
Cat.No. : | CPLX1-305H |
Product Overview : | Recombinant Complexin 1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (154 aa, 17.1 kDa). |
- Specification
- Gene Information
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Cat. No. : | CPLX1-305H |
Description : | Complexin1 belongs to a family of SNARE complex binding proteins that were suggested to be either facilitators or inhibitors of vesicle exocytosis. Complexin 1 exhibits reduced Ca2+-triggered fast neurotransmitter release at hippocampal glutamatergic synapses, indicating that this protein is a positive regulator of transmitter release. In contrast, it inhibits SNARE-mediated liposome and cell fusions in vitro, which lead to the hypothesis that it acts as fusion clamps of synaptic exocytosis. |
Source : | E.coli. |
Formulation : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol. |
Molecular Weight : | 17.1 kDa (154 aa) (Real molecular weight on SDS-PAGE will be shift up). |
Purity : | > 90% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Endotoxin Level : | < 1.0 EU per 1 μg of protein (determined by LAL method). |
Sequence : | MGSSHHHHHH SSGLVPRGSH MEFVMKQALG GATKDMGKML GGDEEKDPDA AKKEEERQEA LRQAEEERKA KYAKMEAERE AVRQGIRDKY GIKKKEEREA EAQAAMEANS EGSLTRPKKA IPPGCGDEVE EEDESILDTV IKYLPGPLQD MLKK |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | CPLX1 |
Synonyms : | CPLX1; complexin 1; CPX1; CPX-I; CPLX1; CPX I; Complexin I; complexin 1 synaphin 2; Synaphin-2. |
Gene ID : | 10815 |
mRNA Refseq : | NM_006651.3 |
Protein Refseq : | NP_006642.1 |
MIM : | 605032 |
UniProt ID : | O14810 |
Chromosome Location : | 4p16.3 |
Pathway : | Synaptic Transmission. |
Function : | syntaxin binding. |
Products Types
◆ Recombinant Protein | ||
CPLX1-1785H | Recombinant Human CPLX1 Protein, GST-tagged | +Inquiry |
CPLX1-1223R | Recombinant Rat CPLX1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CPLX1-167C | Recombinant Cynomolgus Monkey CPLX1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CPLX1-828R | Recombinant Rhesus Macaque CPLX1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CPLX1-1928M | Recombinant Mouse CPLX1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CPLX1-7313HCL | Recombinant Human CPLX1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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