Recombinant Human Estrogen Receptor Binding Site Associated, Antigen, 9, His-tagged EBAG9-385H

Recombinant Human Estrogen Receptor Binding Site Associated, Antigen, 9, His-tagged

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Recombinant Human Estrogen Receptor Binding Site Associated, Antigen, 9, His-tagged

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Cat. No. : EBAG9-385H
Product Overview : Recombinant human EBAG9 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques,23.4 kDa (207 aa).
Description : Estrogen receptor binding site associated antigen 9, also known as EBAG9, is a type III transmembrane protein that is predominantly located in the Golgi. This protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers, such as advanced breast and prostate cancers. As the EBAG9 acts to inhibit the growth of receptor-binding cells and induced apoptosis of immune cells, cancer cells might evade immune surveillance. So immunodetection of EBAG9 expression can be a negative prognostic indicator.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MRSGRGRKLS GDQITLPTTV DYSSVPKQTD VEEWTSWDED APTSVKIEGG NGNVATQQNS LEQLEPDYFK DMTPTIRKTQ KIVIKKREPL NFGIPDGSTG FSSRLAATQD LPFIHQSSEL GDLDTWQENT NAWEEEEDAA WQAEEVLRQQ KLADREKRAA EQQRKKMEKE AQRLMKKEQN KIGVKLS
Formulation : Liquid in 20 mM Tris pH 8.0,1 mM DTT, 2 mM EDTA, 10% glycerol
Purity : > 90% by SDS - PAGE
Concentration : 1 mg/ml (determined by Bradford assay)
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : EBAG9 estrogen receptor binding site associated, antigen, 9 [ Homo sapiens ]
Synonyms : EBAG9; estrogen receptor binding site associated, antigen, 9; EB9; PDAF; RCAS1; estrogen receptor binding site associated antigen 9; cancer associated surface antigen; Receptor-binding cancer antigen expressed on SiSo cells; Cancer-associated surface antigen RCAS1; Estrogen receptor-binding fragment-associated gene 9 protein
Gene ID : 9166
mRNA Refseq : NM_004215
Protein Refseq : NP_004206
MIM : 605772
UniProt ID : O00559
Chromosome Location : 8q23
Function : apoptotic protease activator activity

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