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Recombinant Human Fatty Acid Binding Protein 1, His-tagged

Cat.No. : FABP1-373H
Product Overview : Recombinant human FABP1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques, 16kDa (147aa).
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Cat. No. : FABP1-373H
Description : FABP1 (Fatty acid binding protein1) encodes the fatty acid binding protein found in liver. FABP1 is composed of ten antiparallel β strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acid. This protein binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm; it may be involved in intracellular lipid transport and metabolism.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MSFSGKYQLQ SQENFEAFMK AIGLPEELIQ KGKDIKGVSE IVQNGKHFKF TITAGSKVIQ NEFTVGEECE LETMTGEKVK TVVQLEGDNK LVTTFKNIKS VTELNGDIIT NTMTLGDIVF KRISKRI
Formulation : Liquid. In 20 mM Tris-HCl buffer (pH 8.0)
Purity : > 95% by SDS - PAGE
Concentration : 1 mg/ml (determined by Bradford assay)
Endotoxin Level : < 1.0 EU per 1ug of protein (determined by LAL method)
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : FABP1 fatty acid binding protein 1, liver [ Homo sapiens ]
Synonyms : FABP1; fatty acid binding protein 1, liver; FABPL; L-FABP; Fatty acid-binding protein, liver
Gene ID : 2168
mRNA Refseq : NM_001443
Protein Refseq : NP_001434
MIM : 134650
UniProt ID : P07148
Chromosome Location : 2p11
Function : chromatin binding; lipid binding; transporter activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is FABP1 linked to metabolic disorders? 11/20/2019

Elevated levels of FABP1 are associated with metabolic disorders like obesity and insulin resistance, making it a potential indicator for these conditions.

How is FABP1 involved in fatty acid metabolism? 07/29/2019

FABP1 binds to fatty acids, facilitating their transport and metabolism within liver cells.

Are there other organs where FABP1 is expressed? 03/15/2017

While predominantly found in the liver, FABP1 is also expressed in the small intestine and kidney.

Can FABP1 be used for early detection of liver damage? 08/17/2016

Yes, elevated FABP1 levels in blood or urine may indicate early stages of liver damage, enabling early intervention.

Are there genetic variations influencing FABP1 expression? 08/15/2016

Genetic variations may contribute to differences in FABP1 expression, impacting an individual's susceptibility to certain diseases.

Customer Reviews (3)

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Reviews
07/24/2019

    One notable advantage of using the FABP1 protein is the outstanding technical support provided by its manufacturer.

    05/28/2019

      Its purity and functionality have been extensively tested, ensuring reliable and reproducible results in my research.

      05/22/2019

        The knowledgeable and responsive support team offers valuable assistance and expertise, making troubleshooting and problem-solving much more efficient.

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