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| Cat. No.: | IRF2-366H |
| Product Overview: | Recombinant human IRF2 was expressed in E.coli and purified by using conventional chromatography techniques,15 kDa ( 133 aa). |
| Description: | Interferon regulatory factor (IRF) 2 is a member of the interferon regulatory transcription factor family. IRF-2 is generally regarded as an oncoprotein. Structure of IRF1 and IRF2 are similar. However, its functions are different. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. |
| Sequences of amino acids: | MGSSHHHHHH SSGLVPRGSH MPVERMRMRP WLEEQINSNT IPGLKWLNKE KKIFQIPWMH AARHGWDVEK DAPLFRNWAI HTGKHQPGVD KPDPKTWKAN FRCAMNSLPD IEEVKDKSIK KGNNAFRVYR MLP |
| Formulation: | Liquid. In 20mM Tris pH 8.0, 1 mM DTT, 10% glycerol |
| Purity: | > 95 % by SDS - PAGE |
| Concentration: | 1 mg/ml (determined by Bradford assay) |
| Storage: | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| Gene Name: | IRF2 interferon regulatory factor 2 [ Homo sapiens ] |
| Synonyms: | DKFZp686F0244; IRF-2; interferon regulatory factor 2; IRF2; Interferon regulatory factor-2 |
| Gene ID: | 3660 |
| mRNA Refseq: | NM_002199 |
| Protein Refseq: | NP_002190 |
| MIM: | 147576 |
| UniProt ID: | P14316 |
| Chromosome Location: | 4q34.1-q35.1 |
| Pathway: | |
| Function: | RNA polymerase II transcription factor activity; protein binding; transcription factor activity |
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