Native Human Myeloperoxidase


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Native Human Myeloperoxidase

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Cat.No. : MPO -27H
Product Overview : Myeloperoxidase purified from leucocytes of purulent human sputum which is >98 percent pure.
Description : Myeloperoxidase is a lysosomal protein stored in azurophilic granules of the neutrophil which produces hypochlorous acid from hydrogen peroxide and chloride anion during the neutrophil respiratory burst.
Source : Human sputum
Species : Human
Form : Lyophilized powder
Bio-activity : 155 Units/mg
Molecular Mass : 59,000 Reduced
Unit Definition : 1 unit will decompose 1 umole of H2O2 per minute at pH 7.0 and 25 C using 4-amino-antipyrine as hydrogen donor. Recommended assay buffer: 0.1 M KPO4; pH 7.0
Usage : For in vitro laboratory use only
Notes : Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet.
Stability : Supplied as a lyophilized, salt-free, green soluble powder which is stable for over a year when stored at 5 °C.
Storage : 4°C
Shipping : Cold pack
Gene Name : MPO myeloperoxidase [ Homo sapiens ]
Official Symbol : MPO
Synonyms : MPO; myeloperoxidase;
Gene ID : 4353
mRNA Refseq : NM_000250
Protein Refseq : NP_000241
MIM : 606989
UniProt ID : P05164
Chromosome Location : 17q21.3-q23
Pathway : C-MYB transcription factor network, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; IL23-mediated signaling events, organism-specific biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; Selenium Pathway, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem;
Function : chromatin binding; heme binding; heparin binding; metal ion binding; oxidoreductase activity; peroxidase activity;

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