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Native Rat Fibrinogen, FITC Labeled

Cat.No. : Fgb-64R
Product Overview : Rat fibrinogen amino terminal labeled with fluorescein isothiocyanate (FITC). Prepared from fresh rat plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography.
  • Specification
  • Gene Information
  • Related Products
Source : Rat plasma
Species : Rat
Form : Frozen liquid
Molecular Mass : 340,000
Purity : >95% by SDS-PAGE analysis
Usage : For in vitro laboratory use only. Thaw protein in a 37°C water bath. Aliquot and freeze the unused portion.
Notes : Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet. Keep fibrinogen at 25-37°C, aliquot and flash freeze unused portion.
Storage : -70°C; Protect from light
Concentration : 10 mg/ml
Storage Buffer : 0.02M Sodium Citrate-HCl; pH 7.4
Shipping : Dry ice
Gene Name : Fgb fibrinogen beta chain [ Rattus norvegicus ]
Official Symbol : Fgb
Synonyms : FGB; fibrinogen beta chain; fibrinogen, beta polypeptide; fibrinogen, B beta polypeptide; liver regeneration-related protein LRRG036/LRRG043/LRRG189; Ab1-181; Ab1-216; Ac1-581;
Gene ID : 24366
mRNA Refseq : NM_020071
Protein Refseq : NP_064456
UniProt ID : P14480
Chromosome Location : 2q31-q34
Pathway : Blood Clotting Cascade, organism-specific biosystem; Common Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; GRB2:SOS provides linkage to MAPK signaling for Intergrins, organism-specific biosystem;
Function : chaperone binding; eukaryotic cell surface binding; protein binding, bridging; receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there specific genetic disorders associated with FGB protein abnormalities? 02/21/2023

Yes, congenital fibrinogen disorders, such as afibrinogenemia and hypofibrinogenemia, are genetic disorders characterized by deficient or low FGB protein levels.

What are the potential consequences of low FGB protein levels? 10/07/2022

Low FGB protein levels can result in impaired blood clotting, leading to an increased risk of bleeding and hemorrhage.

How are high FGB protein levels clinically significant? 06/13/2022

High FGB protein levels can be associated with conditions such as inflammation, infection, and certain cancers.

How can FGB protein be used in the diagnosis of coagulation disorders? 06/30/2021

FGB protein levels can be measured to assess the risk of thrombosis or bleeding in patients with coagulation disorders.

What conditions can lead to a decrease in FGB protein levels? 05/22/2017

Conditions such as liver disease, DIC (disseminated intravascular coagulation), and certain genetic disorders can lead to decreased FGB protein levels.

Customer Reviews (3)

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Reviews
03/05/2023

    Their team of experts has been instrumental in addressing any issues or concerns I have encountered during my experiments.

    02/11/2019

      The FGB Protein boasts remarkable stability, ensuring its integrity is maintained during storage and experimentation.

      11/05/2017

        Equally noteworthy is the remarkable technical support provided by the manufacturer.

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