Recombinant Human Fas Ligand Inhibitor, Fc-tagged
Cat.No. : | FAS-37H |
Product Overview : | Produced in HEK 293 cells. The extracellular domain of human Fas (CD95; APO-1)(aa 7-154) is fused to the Fc portion of human IgG1. Purified by multi-step chromatography. |
- Specification
- Gene Information
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Species : | Human |
Tag : | Fc |
Form : | 50 μg lyophilized, contains PBS. |
Molecular Mass : | ~56 kDa |
Endotoxin : | Endotoxin content is<0.1 eu/μg purified protein as determined by lal test.>0.1> |
Purity : | ≥95% as determined by SDS-PAGE. |
Characteristic : | Inhibits the apoptosis-inducing activity of Fas Ligand. Binds FasL. |
Applications : | Functional Application: Inhibition of FAS Ligand activity in human and mouse: The apoptosis-inducing activity of FasL is inhibited by concentrations of 20-100 μg/mL of the fusion protein. |
Usage : | For in vitro research use only. Not for use in diagnostics or in humans. |
Storage : | Store at -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles (activity may decrease). |
Warning : | No warranties, expressed or implied, are made regarding the use of this product. Creative Biomart is not liable for any damage, personal injury, or economic loss caused by this product. |
Gene Name : | FAS Fas (TNF receptor superfamily, member 6) [ Homo sapiens ] |
Official Symbol : | FAS |
Synonyms : | FAS; Fas (TNF receptor superfamily, member 6); APT1, FAS1, TNFRSF6, tumor necrosis factor receptor superfamily, member 6; tumor necrosis factor receptor superfamily member 6; APO 1; CD95; Fas AMA; FAS 827dupA; CD95 antigen; FASLG receptor; apoptosis antigen 1; Delta Fas/APO-1/CD95; APO-1 cell surface antigen; apoptosis-mediating surface antigen FAS; tumor necrosis factor receptor superfamily, member 6; APT1; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; |
Gene ID : | 355 |
mRNA Refseq : | NM_000043 |
Protein Refseq : | NP_000034 |
MIM : | 134637 |
UniProt ID : | P25445 |
Chromosome Location : | 10q24.1 |
Pathway : | Activation of Pro-Caspase 8, organism-specific biosystem; Adipogenesis, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Alzheimers disease, organism-specific biosystem; |
Function : | binding; identical protein binding; kinase binding; protein binding; receptor activity; receptor activity; signal transducer activity; transmembrane signaling receptor activity; tumor necrosis factor-activated receptor activity; |
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◆ Lysates | ||
FAS-1139RCL | Recombinant Rat FAS cell lysate | +Inquiry |
FAS-2185HCL | Recombinant Human FAS cell lysate | +Inquiry |
FAS-2419MCL | Recombinant Mouse FAS cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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