Recombinant Human Fas Ligand Inhibitor, Fc-tagged FAS-37H

Recombinant Human Fas Ligand Inhibitor, Fc-tagged


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Recombinant Human Fas Ligand Inhibitor, Fc-tagged

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Cat.No. : FAS-37H
Product Overview : Produced in HEK 293 cells. The extracellular domain of human Fas (CD95; APO-1)(aa 7-154) is fused to the Fc portion of human IgG1. Purified by multi-step chromatography.
Species : Human
Tag : Fc
Form : 50 μg lyophilized, contains PBS.
Molecular Mass : ~56 kDa
Endotoxin : Endotoxin content is<0.1 eu/μg purified protein as determined by lal test.>
Purity : ≥95% as determined by SDS-PAGE.
Characteristic : Inhibits the apoptosis-inducing activity of Fas Ligand. Binds FasL.
Applications : Functional Application: Inhibition of FAS Ligand activity in human and mouse: The apoptosis-inducing activity of FasL is inhibited by concentrations of 20-100 μg/mL of the fusion protein.
Usage : For in vitro research use only. Not for use in diagnostics or in humans.
Storage : Store at -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles (activity may decrease).
Warning : No warranties, expressed or implied, are made regarding the use of this product. Creative Biomart is not liable for any damage, personal injury, or economic loss caused by this product.
Gene Name : FAS Fas (TNF receptor superfamily, member 6) [ Homo sapiens ]
Official Symbol : FAS
Synonyms : FAS; Fas (TNF receptor superfamily, member 6); APT1, FAS1, TNFRSF6, tumor necrosis factor receptor superfamily, member 6; tumor necrosis factor receptor superfamily member 6; APO 1; CD95; Fas AMA; FAS 827dupA; CD95 antigen; FASLG receptor; apoptosis antigen 1; Delta Fas/APO-1/CD95; APO-1 cell surface antigen; apoptosis-mediating surface antigen FAS; tumor necrosis factor receptor superfamily, member 6; APT1; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6;
Gene ID : 355
mRNA Refseq : NM_000043
Protein Refseq : NP_000034
MIM : 134637
UniProt ID : P25445
Chromosome Location : 10q24.1
Pathway : Activation of Pro-Caspase 8, organism-specific biosystem; Adipogenesis, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Alzheimers disease, organism-specific biosystem;
Function : binding; identical protein binding; kinase binding; protein binding; receptor activity; receptor activity; signal transducer activity; transmembrane signaling receptor activity; tumor necrosis factor-activated receptor activity;

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