Recombinant Mouse Lcn2, His-tagged
Cat.No. : | Lcn2-73M |
Product Overview : | Recombinant mouse Lcn2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
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Description : | Lcn2 also known as neutrophil gelatinase-associated lipocalin, belongs to the calycin superfamily and Lipocalin family. LCN2 is an iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. The binding of LCN2 to bacterial siderophores is important in the innate immune response to bacterial infection. Also LCN2 functions as a growth factor. LCN2 is strongly upregulated during inflammation and is upregulated by interleukin 1 (but not TNF alpha) in humans. |
Source : | E.coli |
Species : | Mouse |
Tag : | His |
Form : | Liquid, In Phosphate buffered saline (pH7.4) containing 10% glycerol, 1mM DTT |
Molecular Mass : | 23.3kDa (203aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSQDSTQNL IPAPSLLTVP LQPDFRSDQF RGRWYVVGLA GNAVQKKTEG SFTMYSTIYE LQENNSYNVT SILVRDQDQG CRYWIRTFVP SSRAGQFTLG NMHRYPQVQS YNVQVATTDY NQFAMVFFRK TSENKQYFKI TLYGRTKELS PELKERFTRF AKSLGLKDDN IIFSVPTDQC IDN |
Purity : | >85% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by Bradford assay) |
Gene Name : | Lcn2 lipocalin 2 [ Mus musculus ] |
Official Symbol : | Lcn2 |
Synonyms : | LCN2; lipocalin 2; neutrophil gelatinase-associated lipocalin; p25; lipocalin-2; SV-40-induced 24P3 protein; secreted inducible protein 24; 24p3; Sip24; AW212229; |
Gene ID : | 16819 |
mRNA Refseq : | NM_008491 |
Protein Refseq : | NP_032517 |
Function : | binding; iron ion binding; protease binding; protein binding; protein homodimerization activity; transporter activity; |
Products Types
◆ Recombinant Protein | ||
LCN2-1151H | Recombinant Human LCN2 Protein, His-tagged | +Inquiry |
LCN2-3024R | Recombinant Rat LCN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
LCN2-1279H | Recombinant Human LCN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
LCN2-797M | Recombinant Mouse LCN2 Protein (Met1-Asn200) | +Inquiry |
Lcn2-1301M | Active Recombinant Mouse Lcn2 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
LCN2-384H | Native Human LCN2 | +Inquiry |
◆ Lysates | ||
LCN2-2895HCL | Recombinant Human LCN2 cell lysate | +Inquiry |
LCN2-2781MCL | Recombinant Mouse LCN2 cell lysate | +Inquiry |
LCN2-538RCL | Recombinant Rat LCN2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionMutations or abnormal expression of the LCN2 protein may be associated with a variety of diseases. For example, in hereditary kidney disease, mutations in the uNGAL gene can lead to kidney damage. In addition, in inflammatory diseases, tumors, and other diseases, the expression level of LCN2 protein may also change.
Studies have shown that the expression level of LCN2 protein is associated with a variety of diseases. For example, in kidney disease, expression levels of the LCN2 protein can be elevated and can be used as one of the biomarkers to assess the extent of kidney damage. In addition, in inflammatory diseases, tumors, and other diseases, the expression level of LCN2 protein can also change.
The interaction between the LCN2 protein and other proteins or molecules is complex. For example, it can participate in lipid metabolism processes by interacting with lipid molecules. In addition, it can interact with other signal transduction molecules to participate in the signal transduction process.
Kidney function can be assessed by measuring the level of uNGAL in urine, and to help diagnose kidney disease, etc. In addition, abnormal levels of LCN2 protein expression can also be used as an indicator to assess the risk and prognosis of other diseases.
The activity of the LCN2 protein is regulated by a variety of factors. First, its expression level is regulated by gene expression. Secondly, its activity is also regulated by a variety of small molecule compounds, hormones and other substances. In addition, the LCN2 protein can also regulate its activity by interacting with other proteins.
LCN2 protein has some association with other biomarkers. For example, in kidney disease, expression levels of uNGAL can be used alongside traditional biomarkers such as creatinine to assess kidney function and degree of impairment. In addition, in diseases such as tumors, expression levels of the LCN2 protein may also change and be associated with other biomarkers.
Customer Reviews (3)
Write a reviewThey have a wide range of products and can always find LCN2 we need.
The reproducibility of LCN2 is almost 100 percent, and the results are very consistent in every experiment or application, which is an important reflection of its excellent quality.
Catalytic activity of LCN2 is really amazing, and every time it is used, it gives an unexpected catalytic effect and its performance is impressive.
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