Active Native Chicken AK1

• Cat.No.: AK1-6667C
• Product Overview: Native Chicken AK1 was purified from chicken muscle.

Specification

• Description: Mutational analysis of the amino acid proline 17 of myokinase from chicken muscle is critical for structural stability, substrate binding and enzyme activity.
• Source: chicken muscle
• Species: Chicken
• Form: essentially salt-free, lyophilized powder
• Bio-activity: essentially salt-free, lyophilized powder, 1,500-3,000 units/mg protein (biuret)
• Unit Definition: One unit will convert 2.0 μmoles of ADP to ATP+AMP per min at pH 7.6 at 37°C.
• Applications: Myokinase from chicken muscle has been used in a study to assess the release of enzymes via acute myositis and neurogenic atrophy in muscles. It has also been used in a study to investigate the development of sarcoplasmic reticulum membranes in chicken pectoralis muscle cells.
• Storage: −20°C

Gene Information

• Gene Name: AK1 adenylate kinase 1 [ Gallus gallus (chicken) ]
• Official Symbol: AK1
• Synonyms: AK1; adenylate kinase 1; adenylate kinase isoenzyme 1; NP_990440.1; EC 2.7.4.3; EC 2.7.4.6
• Gene ID: 396002
• mRNA Refseq: NM_205109
• Protein Refseq: NP_990440
• UniProt ID: P05081
• Chromosome Location: 17
• Pathway: Adenine ribonucleotide biosynthesis, IMP => ADP,ATP; Metabolic pathways; Purine metabolism
• Function: Purine metabolism; adenylate kinase activity; nucleoside diphosphate kinase activity