Recombinant Human SMC3, GST-tagged SMC3-20H

Recombinant Human SMC3, GST-tagged


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Recombinant Human SMC3, GST-tagged

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Cat.No. : SMC3-20H
Product Overview : Recombinant Human SMC3(711 a.a. - 810 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ.
Description : This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.
Source : Wheat germ
Species : Human
Tag : GST
Molecular Mass : 36.63 kDa
Applications : ELISA; WB-Re; AP; Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80ºC. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : SMC3 structural maintenance of chromosomes 3 [ Homo sapiens (human) ]
Official Symbol : SMC3
Synonyms : SMC3; structural maintenance of chromosomes 3; chondroitin sulfate proteoglycan 6 (bamacan) , CSPG6; structural maintenance of chromosomes protein 3; BAM; bamacan; bamacan proteoglycan; HCAP; SMC3L1; SMC-3; SMC protein 3; chromosome-associated polypeptide; chondroitin sulfate proteoglycan 6 (bamacan); basement membrane-associated chondroitin proteoglycan; BMH; CDLS3; CSPG6
Gene ID : 9126
mRNA Refseq : NM_005445
Protein Refseq : NP_005436
MIM : 606062
UniProt ID : Q9UQE7
Chromosome Location : 10q25
Pathway : Cohesin Loading onto Chromatin; Establishment of Sister Chromatid Cohesion; Mitotic Prometaphase; Oocyte meiosis
Function : ATP binding; chromatin binding; mediator complex binding

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