Recombinant Human SMC3, GST-tagged
Cat.No. : | SMC3-20H |
Product Overview : | Recombinant Human SMC3(711 a.a. - 810 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.63 kDa |
AA Sequence : | IDQLMNQMQQIETQQRKFKASRDSI LSEMKMLKEKRQQSEKTFMPKQRSL QSLEASLHAMESTRESLKAELGTDL LSQLSLEDQKRVDALNDEIRQLQQE |
Applications : | ELISA; WB-Re; AP; Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80ºC. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | SMC3 structural maintenance of chromosomes 3 [ Homo sapiens (human) ] |
Official Symbol : | SMC3 |
Synonyms : | SMC3; structural maintenance of chromosomes 3; chondroitin sulfate proteoglycan 6 (bamacan) , CSPG6; structural maintenance of chromosomes protein 3; BAM; bamacan; bamacan proteoglycan; HCAP; SMC3L1; SMC-3; SMC protein 3; chromosome-associated polypeptide; chondroitin sulfate proteoglycan 6 (bamacan); basement membrane-associated chondroitin proteoglycan; BMH; CDLS3; CSPG6 |
Gene ID : | 9126 |
mRNA Refseq : | NM_005445 |
Protein Refseq : | NP_005436 |
MIM : | 606062 |
UniProt ID : | Q9UQE7 |
Chromosome Location : | 10q25 |
Pathway : | Cohesin Loading onto Chromatin; Establishment of Sister Chromatid Cohesion; Mitotic Prometaphase; Oocyte meiosis |
Function : | ATP binding; chromatin binding; mediator complex binding |
Products Types
◆ Recombinant Protein | ||
SMC3-6688H | Recombinant Human SMC3 Protein (Glu995-Glu1181), N-His tagged | +Inquiry |
SMC3-1541H | Recombinant Human SMC3 protein, His & T7-tagged | +Inquiry |
SMC3-2810H | Recombinant Human SMC3, His-tagged | +Inquiry |
SMC3-12720Z | Recombinant Zebrafish SMC3 | +Inquiry |
SMC3-31196TH | Recombinant Human SMC3, His-tagged | +Inquiry |
◆ Lysates | ||
SMC3-1648HCL | Recombinant Human SMC3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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