Active Recombinant Human ACVR1B, Fc Chimera

• Cat.No.: ACVR1B-189H
• Product Overview: Recombinant Human ACVR1B (Accession # AAA60556) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Fc
• Predicted N Terminal: Leu32
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.Immobilized rhActivin RIB/Fc Chimera at 2 µg/mL (100 µL/well) can bind rhCripto with a linear range of 0.8 - 100 ng/mL.
• Molecular Mass: Recombinant Human ACVR1B, Fc Chimera has a calculated MW of 37.5 kDa (monomer). In SDS-PAGE migrates as 45-50 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: ACVR1B activin A receptor, type IB [ Homo sapiens ]
• Official Symbol: ACVR1B
• Synonyms: ACVR1B; activin A receptor, type IB; ACVRLK4; activin receptor type-1B; ActRIB; ALK4; SKR2; activin receptor-like kinase 4; activin A receptor, type II-like kinase 4; serine/threonine-protein kinase receptor R2; ACTRIB
• Gene ID: 91
• mRNA Refseq: NM_004302
• Protein Refseq: NP_004293
• MIM: 601300
• UniProt ID: P36896
• Chromosome Location: 12q13