Recombinant Human TNFRSF11B, Fc Chimera TNFRSF11B-211H

Recombinant Human TNFRSF11B, Fc Chimera

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Recombinant Human TNFRSF11B, Fc Chimera

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Cat.No. : TNFRSF11B-211H
Product Overview : Recombinant Human TNFRSF11B (Accession # AAB53709) was produced in Spodoptera frugiperda, Sf 21 (baculovirus)-derived.
Source : Baculovirus Sf 21 Insect cells
Species : Human
Tag : Fc Chimera
Predicted N Terminal : Glu22
Form : Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity : Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL.The ED50 for this effect is typically 8 - 24 ng/mL in the presence of 12 ng/mL recombinant human TRAIL.
Molecular Mass : Recombinant Human TNFRSF11B, Fc Chimera has a calculated MW of 71 kDa (monomer). In SDS-PAGE migrates as 77 kDa, reducing conditions.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : TNFRSF11B tumor necrosis factor receptor superfamily, member 11b [ Homo sapiens ]
Official Symbol : TNFRSF11B
Synonyms : TNFRSF11B; tumor necrosis factor receptor superfamily, member 11b; OPG, osteoprotegerin; tumor necrosis factor receptor superfamily member 11B; OCIF; TR1; osteoprotegerin; osteoclastogenesis inhibitory factor; OPG; MGC29565;
Gene ID : 4982
mRNA Refseq : NM_002546
Protein Refseq : NP_002537
MIM : 602643
UniProt ID : O00300
Chromosome Location : 8q24

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