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Active Recombinant Human TNFRSF11B

Cat.No. : TNFRSF11B-212H
Product Overview : Recombinant Human TNFRSF11B (Accession # AAB53709.1) Glu22-Leu401 was produced in Mouse myeloma cell line, NS0-derived.
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  • Gene Information
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Source : Mammalian cells
Species : Human
Predicted N Terminal : Glu22
Form : Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity : Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL.The ED50 for this effect is typically 8-24 ng/mL in the presence of 12 ng/mL cross-linked Recombinant Human TRAIL/TNFSF10.
Molecular Mass : Recombinant Human TNFRSF11B has a calculated MW of 43.5 kDa (monomer). In SDS-PAGE migrates as 55 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : TNFRSF11B tumor necrosis factor receptor superfamily, member 11b [ Homo sapiens ]
Official Symbol : TNFRSF11B
Synonyms : TNFRSF11B; tumor necrosis factor receptor superfamily, member 11b; OPG, osteoprotegerin; tumor necrosis factor receptor superfamily member 11B; OCIF; TR1; osteoprotegerin; osteoclastogenesis inhibitory factor; OPG; MGC29565;
Gene ID : 4982
mRNA Refseq : NM_002546
Protein Refseq : NP_002537
MIM : 602643
UniProt ID : O00300
Chromosome Location : 8q24

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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