Active Recombinant Human NT5E, His-tagged
Cat.No. : | NT5E-343H |
Product Overview : | Recombinant Human NT5E (Accession # AAH65937) Trp27-Lys547, fused with a C-terminal 6-His tag, was produced in Chinese Hamster Ovary cell line, CHO-derived. |
- Specification
- Gene Information
- Related Products
Source : | CHO cells |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Trp27 |
Form : | Supplied as a 0.2 µm filtered solution in Tris, NaCl, CaCl2 and Glycerol. |
Bio-activity : | Measured by its ability to hydrolyze the 5"-phosphate group from the substrate adenosine-5"-monophosphate (AMP). The orthophosphate product is measured by a Malachite Green Phosphate Detection Kit .The specific activity is >15,000 pmol/min/µg, as measured under the described conditions. |
Molecular Mass : | Recombinant Human NT5E, His-tagged has a calculated MW of 59 kDa. In SDS-PAGE migrates as 61-62 kDa, reducing conditions. |
Purity : | >90%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name : | NT5E 5-nucleotidase, ecto (CD73) [ Homo sapiens ] |
Official Symbol : | NT5E |
Synonyms : | NT5E; 5-nucleotidase, ecto (CD73); 5 nucleotidase (CD73) , NT5; 5-nucleotidase; CD73; eN; eNT; 5-NT; ecto-5-nucleotidase; Purine 5-Prime-Nucleotidase; NT; NT5; NTE; E5NT; |
Gene ID : | 4907 |
mRNA Refseq : | NM_001204813 |
Protein Refseq : | NP_001191742 |
MIM : | 129190 |
UniProt ID : | P21589 |
Chromosome Location : | 6q14-q21 |
Products Types
◆ Recombinant Protein | ||
NT5E-1160H | Recombinant Human NT5E Protein, His-tagged | +Inquiry |
NT5E-1302H | Recombinant Human NT5E Protein, GST-tagged | +Inquiry |
NT5E-8848C | Recombinant Cynomolgus NT5E, His tagged | +Inquiry |
NT5E-580H | Active Recombinant Human NT5E, Fc-tagged | +Inquiry |
NT5E-3859HB | Recombinant Human NT5E protein, His-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
NT5E-1082RCL | Recombinant Rat NT5E cell lysate | +Inquiry |
NT5E-1153CCL | Recombinant Cynomolgus NT5E cell lysate | +Inquiry |
NT5E-2073HCL | Recombinant Human NT5E cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
- Reviews
Q&As (5)
Ask a questionYes, elevated levels of NT5E have been observed in various diseases, making it a potential biomarker for conditions such as cancer and autoimmune disorders.
NT5E-generated adenosine has anti-inflammatory effects, and modulating NT5E activity is being explored as a potential therapeutic strategy for inflammatory conditions.
Yes, NT5E is implicated in autoimmune diseases, and targeting its activity is being investigated for potential therapeutic interventions.
As of my last knowledge update in January 2022, there were no FDA-approved drugs specifically targeting NT5E, but research in this area is ongoing.
NT5E-generated adenosine is neuroprotective, and research is exploring its potential in the treatment of neurodegenerative disorders.
Customer Reviews (3)
Write a reviewthe manufacturer's support plays a crucial role in the successful implementation of trials involving the NT5E protein.
The manufacturer maintains stringent quality control measures to ensure the purity and stability of the protein, minimizing experimental variability and maximizing the accuracy of the data obtained.
Their responsiveness to inquiries and willingness to address concerns contribute to a smooth and productive research experience.
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