Active Recombinant Human MMEL1, His-tagged

• Cat.No.: MMEL1-384H
• Product Overview: Recombinant Human MMEL1 (Accession # AAL08942) Gly69-Trp770, fused with an N-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: His
• Predicted N Terminal: His
• Form: Supplied as a 0.2 µm filtered solution in Tris, NaCl and ZnCl2.
• Bio-activity: Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPPGFSAFK(Dnp)-OH .The specific activity is >250 pmol/min/µg, as measured under the described conditions.
• Molecular Mass: Recombinant Human MMEL1, His-tagged has a calculated MW of 82 kDa. In SDS-PAGE migrates as 99 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: MMEL1 membrane metallo-endopeptidase-like 1 [ Homo sapiens ]
• Official Symbol: MMEL1
• Synonyms: MMEL1; membrane metallo-endopeptidase-like 1; membrane metallo endopeptidase like 2 , MMEL2; NEPII; NL1; NL2; SEP; NEP2(m); neprilysin-2; neprilysin II; zinc metallopeptidase; soluble secreted endopeptidase; membrane metallo-endopeptidase-like 2; NEP2; MMEL2; MGC119454; MGC119455; MGC119456
• Gene ID: 79258
• mRNA Refseq: NM_033467
• Protein Refseq: NP_258428
• UniProt ID: Q495T6
• Chromosome Location: 1p36