Recombinant Human IL6R, His-tagged IL6R-428H

Recombinant Human IL6R, His-tagged

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Recombinant Human IL6R, His-tagged

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Cat.No. : IL6R-428H
Product Overview : Recombinant Human IL6R (Accession # ACC04617) Ala22-Val346, fused with a C-terminal 10-His tag, was produced in Mouse myeloma cell line, NS0-derived.
Source : NSO cells
Species : Human
Tag : His
Predicted N Terminal : Ala22
Form : Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity : Measured by its ability to inhibit Wnt-3a-induced alkaline phosphatase production by MC3T3-E1 mouse preosteoblast cells.The ED50 for this effect is typically 4-20 µg/mL, in the presence of 10 ng/mL of Recombinant Mouse Wnt-3a.Optimal dilutions should be determined by each laboratory for each application.
Molecular Mass : Recombinant Human IL6R, His-tagged has a calculated MW of 38.9 kDa. In SDS-PAGE migrates as 55 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 250 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : IL6R interleukin 6 receptor [ Homo sapiens ]
Official Symbol : IL6R
Synonyms : IL6R; interleukin 6 receptor; interleukin-6 receptor subunit alpha; CD126; IL-6R 1; CD126 antigen; membrane glycoprotein 80; IL-6 receptor subunit alpha; gp80; IL6RA; IL-6RA; IL-6R-1; MGC104991;
Gene ID : 3570
mRNA Refseq : NM_000565
Protein Refseq : NP_000556
MIM : 147880
UniProt ID : P08887
Chromosome Location : 1q21

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