Active Recombinant Mouse Tgfbr1, Fc Chimera

• Cat.No.: Tgfbr1-439M
• Product Overview: Recombinant Mouse Tgfbr1 (Accession # BAA05023) was produced in Spodoptera frugiperda, Sf 21 (baculovirus)-derived.

Specification

• Source: Baculovirus Sf 21 Insect cells
• Species: Mouse
• Tag: Fc Chimera
• Predicted N Terminal: Ala21 & Thr22
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.When Recombinant Rat Endoglin/CD10^5 Fc Chimera or Recombinant Mouse Endoglin/CD10^5 Fc Chimera is immobilized at 2 µg/mL (100 µL/well), the concentration of Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera that produces 50% of the optimal binding response is found to be approximately 0.25-1.25 µg/mL.
• Molecular Mass: Recombinant Mouse Tgfbr1, Fc Chimera has a calculated MW of 37.5 kDa (monomer). In SDS-PAGE migrates as 40-50 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Tgfbr1 transforming growth factor, beta receptor I [ Mus musculus ]
• Official Symbol: Tgfbr1
• Synonyms: TGFBR1; transforming growth factor, beta receptor I; TGF-beta receptor type-1; ESK2; TGFR-1; TGF-beta receptor type I; transforming growth factor-beta receptor type I; ALK5; Alk-5; TbetaRI; AU017191; TbetaR-I
• Gene ID: 21812
• mRNA Refseq: NM_009370
• Protein Refseq: NP_033396