Active Recombinant Human TFRC, His-tagged
Cat.No. : | TFRC-465H |
Product Overview : | Recombinant Human TFRC (Accession # CAA25527) Cys89-Phe760, fused with an N-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived. |
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Source : | Mammalian cells |
Species : | Human |
Tag : | His |
Predicted N Terminal : | His |
Form : | Lyophilized from a 0.2 µm filtered solution in Tris and NaCl with Trehalose. |
Bio-activity : | Measured by its binding ability in a functional ELISA.When human Holo-Transferrin is coated at 0.5 µg/mL (100 µL/well), the concentration of rhTfR that produces 50% of the optimal binding response is found to be approximately 3-12 ng/mL. |
Molecular Mass : | Recombinant Human TFRC, His-tagged has a calculated MW of 76 kDa. In SDS-PAGE migrates as 76-85 kDa, reducing conditions. |
Purity : | >90%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name : | TFRC transferrin receptor (p90, CD71) [ Homo sapiens ] |
Official Symbol : | TFRC |
Synonyms : | TFRC; transferrin receptor (p90, CD71); transferrin receptor protein 1; CD71; TFR1; T9; TR; TFR; p90; TRFR; |
Gene ID : | 7037 |
mRNA Refseq : | NM_001128148 |
Protein Refseq : | NP_001121620 |
MIM : | 190010 |
UniProt ID : | P02786 |
Chromosome Location : | 3q26.2-qter |
Products Types
◆ Recombinant Protein | ||
TFRC-2124H | Recombinant Human TFRC Protein, His-tagged | +Inquiry |
TFRC-296H | Recombinant Human TFRC Protein (ECD), His-tagged(C-ter) | +Inquiry |
TFRC-1247H | Recombinant Human TFRC Protein, His-tagged | +Inquiry |
TFRC-467H | Recombinant Human TFRC Protein, His-tagged | +Inquiry |
TFRC-12H | Recombinant Human TFRC Protein (101-760aa), C-His-tagged | +Inquiry |
◆ Native Protein | ||
TFRC-16H | Native Human Apotransferrin Protein | +Inquiry |
TFRC-69H | Native Human Apotransferrin | +Inquiry |
TFRC-249H | Native Human Transferrin Receptor | +Inquiry |
◆ Lysates | ||
TFRC-950CCL | Recombinant Cynomolgus TFRC cell lysate | +Inquiry |
TFRC-1813MCL | Recombinant Mouse TFRC cell lysate | +Inquiry |
TFRC-2058HCL | Recombinant Human TFRC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, TFRC's presence on cell surfaces has been exploited for the development of targeted drug delivery systems, especially for delivering drugs to cancer cells.
Yes, some experimental therapies aim to target TFRC on cancer cells, such as antibody-drug conjugates (ADCs) and small-molecule inhibitors.
Yes, dysregulation of TFRC expression or function can be associated with various medical conditions, including anemia, cancer, and neurodegenerative diseases.
Researchers use techniques like immunohistochemistry and molecular assays to study TFRC expression levels in patient samples. This helps in diagnosis and prognosis.
Understanding TFRC expression in the context of anemia can help identify the underlying causes and guide treatment strategies to improve iron uptake.
Customer Reviews (3)
Write a reviewIn addition to the advantages of GAD1 protein itself, the manufacturer can play a crucial role in supporting the research efforts.
This quality control is essential for obtaining reliable and reproducible data, as any variability in protein quality can introduce confounding factors into experiments.
This versatility enables researchers to explore GAD1's function and role in a range of biological processes, making it a valuable tool across diverse research fields.
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