Active Recombinant Mouse Gas6, His-tagged
Cat.No. : | Gas6-483M |
Product Overview : | Recombinant Mouse Gas6 (Accession # CAA42507) Ala46-Pro673, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived. |
- Specification
- Gene Information
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Source : | Mammalian cells |
Species : | Mouse |
Tag : | His |
Predicted N Terminal : | Ala46 & Tyr47 |
Form : | Lyophilized from a 0.2 µm filtered solution in PBS. |
Bio-activity : | Measured by its ability to down regulate the expression of Axl in DU145 human prostate carcinoma cells. Mishra, A. et al. (2012) Mol. Cancer Res. 10:703.The ED50 for this effect is typically 20-100 ng/mL. |
Molecular Mass : | Recombinant Mouse Gas6, His-tagged has a calculated MW of 71 kDa. In SDS-PAGE migrates as 78-94 kDa, reducing conditions. |
Purity : | >95%, by SDS-PAGE with silver staining. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name : | Gas6 growth arrest specific 6 [ Mus musculus ] |
Official Symbol : | Gas6 |
Synonyms : | GAS6; growth arrest specific 6; growth arrest-specific protein 6; GAS 6; AXL receptor tyrosine kinase ligand; Gas-6; |
Gene ID : | 14456 |
mRNA Refseq : | NM_019521 |
Protein Refseq : | NP_062394 |
MIM : |
Products Types
◆ Recombinant Protein | ||
GAS6-3014H | Recombinant Human GAS6 Protein, His (Fc)-Avi-tagged | +Inquiry |
GAS6-546H | Active Recombinant Human GAS6 Protein(Leu136~Phe311), His-tagged | +Inquiry |
GAS6-288TH | Recombinant Human GAS6 full-length, GST-tagged | +Inquiry |
GAS6-898M | Recombinant Mouse GAS6 Protein (Met1-Pro674), His-tagged | +Inquiry |
Gas6-3478M | Recombinant Mouse Gas6 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
GAS6-6017HCL | Recombinant Human GAS6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionExpression level of GAS6 protein is associated with the occurrence and progression of cardiovascular disease. For example, in atherosclerotic lesions, the expression level of GAS6 protein can change and may promote the development of the lesion. In addition, GAS6 protein can also be used as one of the biomarkers of cardiovascular disease prognosis.
The protein has some association with other biomarkers. For example, in breast cancer, the expression level of GAS6 protein can be used to assess the prognosis and treatment effect of breast cancer together with biomarkers such as ERBB2 and EGFR.
GAS6 protein has a role in tumor treatment. For example, by regulating the expression level of GAS6 protein, tumor cells can be enhanced to radiotherapy or chemotherapy. In addition, GAS6 protein can also be used as a target for targeted therapies such as antibody-drug conjugates.
Regulating the expression level of GAS6 protein can influence the development of cardiovascular disease and the treatment effect. For example, certain drugs can inhibit the development of atherosclerotic lesions by inhibiting the expression level of the GAS6 protein. furthermore
It can be used to aid in tumor diagnosis and prognosis by measuring the expression level of GAS6 protein. For example, a low-expression GAS6 protein may predict a worse prognosis and greater tumor aggressiveness.
Expression level of GAS6 protein is related to tumor genesis, development and prognosis. For example, in patients with non-small cell lung cancer, low expression of the GAS6 protein was associated with poorer survival and higher metastasis rates. In addition, GAS6 protein can also serve as a biomarker to predict tumor response to specific treatments.
Customer Reviews (3)
Write a reviewGAS6 is a treasure in the field of scientific research due to its high catalytic efficiency, high safety and high expression level.
The short half-life and high clearance of GAS6 make its action more rapid and transient, allowing for a rapid therapeutic effect.
Green production process of GAS6 is very advanced and uses the most environmentally friendly production process and is very environmentally friendly.
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