Active Recombinant Mouse Tek, Fc Chimera
Cat.No. : | Tek-490M |
Product Overview : | Recombinant Mouse Tek (Accession # CAA47857) was produced in Mouse myeloma cell line, NS0-derived. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian cells |
Species : | Mouse |
Tag : | Fc Chimera |
Predicted N Terminal : | Ala23 |
Form : | Lyophilized from a 0.2 µm filtered solution in PBS. |
Bio-activity : | Measured by its binding ability in a functional ELISA.Immobilized rmTie-2/Fc Chimera at 4 µg/mL (100 µL/well) can bind rhAngiopoietin-2 with a linear range of 2 - 50 ng/mL. |
Molecular Mass : | Recombinant Mouse Tek, Fc Chimera has a calculated MW of 107.2 kDa (monomer). In SDS-PAGE migrates as 125-135 kDa, reducing conditions. |
Purity : | >90%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name : | Tek endothelial-specific receptor tyrosine kinase [ Mus musculus ] |
Official Symbol : | Tek |
Synonyms : | TEK; endothelial-specific receptor tyrosine kinase; angiopoietin-1 receptor; STK1; mTIE2; p140 TEK; endothelial tyrosine kinase; tyrosine-protein kinase receptor TEK; tunica interna endothelial cell kinase; tyrosine-protein kinase receptor TIE-2; tyrosine kinase with Ig and EGF homology domains-2; Hyk; Tie2; tie-2; Cd202b; AA517024; |
Gene ID : | 21687 |
mRNA Refseq : | NM_013690 |
Protein Refseq : | NP_038718 |
MIM : |
Products Types
◆ Recombinant Protein | ||
Tek-28R | Recombinant Rat Tek Protein, His (Fc)-Avi-tagged | +Inquiry |
TEK-7296H | Active Recombinant Human TEK protein(Gln771-Ala1124), His&GST-tagged | +Inquiry |
TEK-2758H | Recombinant Human TEK Protein, His-tagged | +Inquiry |
TEK-036H | Active Recombinant Human TEK Protein, hIgG/His-tagged | +Inquiry |
TEK-996R | Recombinant Rhesus TEK Protein (Met1-Lys745), His-tagged | +Inquiry |
◆ Lysates | ||
TEK-415HCL | Recombinant Human TEK cell lysate | +Inquiry |
TEK-1511MCL | Recombinant Mouse TEK cell lysate | +Inquiry |
TEK-1707RCL | Recombinant Rat TEK cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThe TEK gene is crucial for vascular development during embryogenesis, coordinating with other genes and signaling pathways to ensure proper formation of the vascular system.
The TEK gene is implicated in pathological angiogenesis in diseases like cancer, where dysregulation of TIE2 signaling can contribute to aberrant blood vessel formation.
The TEK gene, through TIE2 signaling, regulates vascular permeability by influencing the integrity of endothelial cell junctions and controlling the passage of molecules across blood vessels.
The TEK gene contributes to the maintenance of vascular quiescence by suppressing endothelial cell activation and inflammation, preserving the stability of blood vessels.
The TEK gene, through TIE2 signaling, influences immune responses by modulating interactions between endothelial cells and immune cells during vascular inflammation.
Customer Reviews (3)
Write a reviewOutstanding service! Staff expertise helped us choose the perfect protein.
Seamless delivery process—ordered, received, and ready for experiments.
Courteous and efficient customer service made our purchase hassle-free.
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