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Active Recombinant Mouse Tek, Fc Chimera

Cat.No. : Tek-490M
Product Overview : Recombinant Mouse Tek (Accession # CAA47857) was produced in Mouse myeloma cell line, NS0-derived.
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  • Gene Information
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Source : Mammalian cells
Species : Mouse
Tag : Fc Chimera
Predicted N Terminal : Ala23
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its binding ability in a functional ELISA.Immobilized rmTie-2/Fc Chimera at 4 µg/mL (100 µL/well) can bind rhAngiopoietin-2 with a linear range of 2 - 50 ng/mL.
Molecular Mass : Recombinant Mouse Tek, Fc Chimera has a calculated MW of 107.2 kDa (monomer). In SDS-PAGE migrates as 125-135 kDa, reducing conditions.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : Tek endothelial-specific receptor tyrosine kinase [ Mus musculus ]
Official Symbol : Tek
Synonyms : TEK; endothelial-specific receptor tyrosine kinase; angiopoietin-1 receptor; STK1; mTIE2; p140 TEK; endothelial tyrosine kinase; tyrosine-protein kinase receptor TEK; tunica interna endothelial cell kinase; tyrosine-protein kinase receptor TIE-2; tyrosine kinase with Ig and EGF homology domains-2; Hyk; Tie2; tie-2; Cd202b; AA517024;
Gene ID : 21687
mRNA Refseq : NM_013690
Protein Refseq : NP_038718
MIM :

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does the TEK gene influence vascular development during embryogenesis, and what are the key molecular players involved? 09/26/2021

The TEK gene is crucial for vascular development during embryogenesis, coordinating with other genes and signaling pathways to ensure proper formation of the vascular system.

What role does the TEK gene play in pathological angiogenesis, particularly in diseases like cancer? 06/15/2020

The TEK gene is implicated in pathological angiogenesis in diseases like cancer, where dysregulation of TIE2 signaling can contribute to aberrant blood vessel formation.

How does the TEK gene contribute to the modulation of vascular permeability? 12/07/2019

The TEK gene, through TIE2 signaling, regulates vascular permeability by influencing the integrity of endothelial cell junctions and controlling the passage of molecules across blood vessels.

How does the TEK gene contribute to the maintenance of vascular quiescence, and what molecular processes are involved? 08/04/2019

The TEK gene contributes to the maintenance of vascular quiescence by suppressing endothelial cell activation and inflammation, preserving the stability of blood vessels.

How does the TEK gene participate in the regulation of immune responses in the context of vascular inflammation? 03/05/2018

The TEK gene, through TIE2 signaling, influences immune responses by modulating interactions between endothelial cells and immune cells during vascular inflammation.

Customer Reviews (3)

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Reviews
06/07/2020

    Outstanding service! Staff expertise helped us choose the perfect protein.

    10/31/2019

      Seamless delivery process—ordered, received, and ready for experiments.

      03/14/2018

        Courteous and efficient customer service made our purchase hassle-free.

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