Active Recombinant Rat Il6st, Fc Chimera

• Cat.No.: Il6st-539R
• Product Overview: Recombinant Rat Il6st (Accession # EDM10349) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Species: Rat
• Source: Mammalian Cells
• Tag: Fc
• Predicted N Terminal: No results obtained: Gln23 predicted & Tyr30
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit the IL-6 R alpha enhancement of IL-6 activity on M1 mouse myeloid leukemia cells. Saito, T. et al. (1991) J. Immunol. 147:168.The ED50 for this effect is typically 5 - 30 ng/mL in the presence of 10 ng/mL recombinant human (rh) IL-6 R alpha and 20 ng/mL of rhIL-6.
• Molecular Mass: Recombinant Rat Il6st, Fc Chimera has a calculated MW of 94 kDa (monomer). In SDS-PAGE migrates as 105-130 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Il6st interleukin 6 signal transducer [ Rattus norvegicus ]
• Official Symbol: Il6st
• Synonyms: IL6ST; interleukin 6 signal transducer; interleukin-6 receptor subunit beta; IL-6R subunit beta; membrane glycoprotein 130; IL-6 receptor subunit beta; interleukin-6 signal transducer; oncostatin-M receptor subunit alpha; Gp130; Ac1055; Il-6rb
• Gene ID: 25205
• mRNA Refseq: NM_001008725
• Protein Refseq: NP_001008725