Active Recombinant Rat Il6st, Fc Chimera
Cat.No. : | Il6st-539R |
Product Overview : | Recombinant Rat Il6st (Accession # EDM10349) was produced in Mouse myeloma cell line, NS0-derived. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian cells |
Species : | Rat |
Tag : | Fc Chimera |
Predicted N Terminal : | No results obtained: Gln23 predicted & Tyr30 |
Form : | Lyophilized from a 0.2 µm filtered solution in PBS. |
Bio-activity : | Measured by its ability to inhibit the IL-6 R alpha enhancement of IL-6 activity on M1 mouse myeloid leukemia cells. Saito, T. et al. (1991) J. Immunol. 147:168.The ED50 for this effect is typically 5 - 30 ng/mL in the presence of 10 ng/mL recombinant human (rh) IL-6 R alpha and 20 ng/mL of rhIL-6. |
Molecular Mass : | Recombinant Rat Il6st, Fc Chimera has a calculated MW of 94 kDa (monomer). In SDS-PAGE migrates as 105-130 kDa, reducing conditions. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name : | Il6st interleukin 6 signal transducer [ Rattus norvegicus ] |
Official Symbol : | Il6st |
Synonyms : | IL6ST; interleukin 6 signal transducer; interleukin-6 receptor subunit beta; IL-6R subunit beta; membrane glycoprotein 130; IL-6 receptor subunit beta; interleukin-6 signal transducer; oncostatin-M receptor subunit alpha; Gp130; Ac1055; Il-6rb; |
Gene ID : | 25205 |
mRNA Refseq : | NM_001008725 |
Protein Refseq : | NP_001008725 |
MIM : |
Products Types
◆ Recombinant Protein | ||
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IL6ST-1055H | Recombinant Human IL6ST Protein, His-tagged | +Inquiry |
IL6ST-5171H | Recombinant Human IL6ST Protein, GST-tagged | +Inquiry |
IL6ST-1380H | Acitve Recombinant Human IL6ST protein(Met1-Ile618), His&hFc-tagged | +Inquiry |
Il6st-4092R | Active Recombinant Rat Il6st protein(Met4-Glu618), His-tagged | +Inquiry |
◆ Lysates | ||
IL6ST-935HCL | Recombinant Human IL6ST cell lysate | +Inquiry |
IL6ST-1882RCL | Recombinant Rat IL6ST cell lysate | +Inquiry |
IL6ST-001MCL | Recombinant Mouse IL6ST cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe activity of IL6ST is usually detected by cell differentiation and proliferation assay.
IL6ST may be used in the future to treat pulmonary fibrosis, chronic pulmonary obstruction, rheumatoid arthritis, and other chronic kidney diseases.
IL6ST is involved in various inflammatory responses and cell differentiation processes.
The physical and chemical properties of IL6ST include molecular weight, voltammetry potential, structure and stability.
The study of IL6ST helps us to better understand the disease mechanism involved in IL6ST, and provides new ideas and means for disease treatment.
The IL6ST is usually prepared by transforming E. coli into an expression vector and making it express the IL6ST protein.
Customer Reviews (3)
Write a reviewIL6ST proteins can be functionally enhanced or altered by protein modification techniques.
As an immunotherapy drug, it has good effect and high safety.
Has a good inhibitory effect on cell proliferation and survival.
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