Recombinant Rat Eng, Fc Chimera Eng-638R

Recombinant Rat Eng, Fc Chimera


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Recombinant Rat Eng, Fc Chimera

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Cat.No. : Eng-638R
Product Overview : Recombinant Rat Eng (Accession # NP_001010968) was produced in Mouse myeloma cell line, NS0-derived.
Source : NSO cells
Species : Rat
Tag : Fc Chimera
Predicted N Terminal : Glu26
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its binding ability in a functional ELISA.When Recombinant Rat Endoglin/CD10^5 Fc Chimera is immobilized at 2 µg/mL (100 µL/well), the concentration of Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera that produces 50% of the optimal binding response is found to be approximately 0.25-1.25 µg/mL.Measured by its ability to inhibit BMP-10-induced alkaline phosphatase production by MC3T3-E1 mouse preosteoblast cells.The ED50 for this effect is typically 0.15-0.75 µg/mL.
Molecular Mass : Recombinant Rat Eng, Fc Chimera has a calculated MW of 87.0 kDa (monomer). In SDS-PAGE migrates as 100-115 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : Eng endoglin [ Rattus norvegicus ]
Official Symbol : Eng
Synonyms : ENG; endoglin; MGC124909;
Gene ID : 497010
mRNA Refseq : NM_001010968
Protein Refseq : NP_001010968

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