Recombinant Human LTBR, Fc Chimera LTBR-746H

Recombinant Human LTBR, Fc Chimera

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Recombinant Human LTBR, Fc Chimera

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Cat.No. : LTBR-746H
Product Overview : Recombinant Human LTBR (Accession # NP_002333) was produced in Chinese Hamster Ovary cell line, CHO-derived.
Source : CHO cells
Species : Human
Tag : Fc Chimera
Predicted N Terminal : Ser28
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its ability to inhibit Lymphotoxin alpha 1/beta 2-induced IL-8 secretion in A375 human melanoma cells. Degli-Esposti, M. et al. (1997) J. Immunol. 158:1756.The ED50 for this effect is typically 2-10 ng/mL in the presence of 10 ng/mL of Recombinant Human Lymphotoxin alpha 1/beta 2.
Molecular Mass : Recombinant Human LTBR, Fc Chimera has a calculated MW of 48.5 kDa (monomer). In SDS-PAGE migrates as 60-66 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) [ Homo sapiens ]
Official Symbol : LTBR
Synonyms : LTBR; lymphotoxin beta receptor (TNFR superfamily, member 3); D12S370; tumor necrosis factor receptor superfamily member 3; TNF R III; TNFCR; TNFR RP; TNFR2 RP; TNFRSF3; TNF-RIII; TNFR-III; lymphotoxin B receptor; lymphotoxin-beta receptor; TNFR superfamily, member 3; tumor necrosis factor C receptor; tumor necrosis factor receptor type III; tumor necrosis factor receptor 2-related protein; tumor necrosis factor receptor superfamily, member 3; CD18; TNFR-RP; TNFR2-RP; LT-BETA-R; TNF-R-III;
Gene ID : 4055
mRNA Refseq : NM_002342
Protein Refseq : NP_002333
MIM : 600979
UniProt ID : P36941
Chromosome Location : 12p13

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