Recombinant Human IL2 IL2-2741H

Recombinant Human IL2


Home / Products / Recombinant Proteins / Recombinant Human IL2

Recombinant Human IL2

IL2 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : IL2-2741H
Product Overview : Recombinant human IL-2 produced in Yeast is a single, non-glycosylated, polypeptide chain containing 133 amino acids, one pair of disulfide bond and with 125 Cys. aa. mutated to Ala aa, having a molecular mass of approximately 15.4kDa.
Description : Human IL-2 (also known as TCGF) is an about 15.4KD factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active. Recombinant human IL-2 is biologically active and can promote proliferation of T lymphocytes in culture.
Source : Yeast
Species : Human
Form : Lyophilized from a 0.2μm filtered solution in 10mM Phosphate buffer containing 0.3% human serum albumin.
Bio-activity : Measured in a cell proliferation assay using an IL-2 dependent Mouse cytotoxic T cell line, CTLL-2. The specific activity shall be not less than 3×10^7 IU/mg.
Endotoxin : ≤1EU/μg, determined by the LAL method
Purity : ≥97%, as determined by SDS-PAGE and HPLC method.
Storage : Lyophilized samples are stable for greater than six months from date of receipt at -20 centigrade to -70 centigrade. The reconstituted samples can be stored under sterile conditions at 2-8 centigrade for one month or at -20 centigrade to -70 centigrade for three months without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial, to prepare a stock solution of not less than 1μg/ml.
Gene Name : IL2 interleukin 2 [ Homo sapiens ]
Official Symbol : IL2
Synonyms : IL-2; TCGF; lymphokine; interleukin-2; T cell growth factor; aldesleukin; involved in regulation of T-cell clonal expansion
Gene ID : 3558
mRNA Refseq : NM_000586
Protein Refseq : NP_000577
MIM : 147680
UniProt ID : P60568
Chromosome Location : 4q26-q27
Pathway : AhR pathway, organism-specific biosystem; Autoimmune thyroid disease, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem
Function : carbohydrate binding; cytokine activity; glycosphingolipid binding

Online Inquiry

  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy