"PTPN11" Related Products


Recombinant Human PTPN11 Protein, His-tagged

Cat.No.: PTPN11-519H
Product Overview: Recombinant Human PTPN11 (Accession # NP_002825) Ser2-Arg593, fused with an N-terminal 6-His tag, was produced in E. coli.
Source: E. coli
Species: Human
Tag: His
Predicted N Terminal: His
Form: Supplied as a 0.2 µm filtered solution in Tris, NaCl, Glycerol and DTT.
Bio-activity: Measured by its ability to dephosphorylate a tyrosine residue in a peptide containing the EGFR Y992 phosphorylation site.The specific activity is >1.2 µmol/min/mg, measured under the described conditions.
Molecular Mass: Recombinant Human PTPN11, His-tagged has a calculated MW of 69 kDa. In SDS-PAGE migrates as 63-70 kDa, reducing conditions.
Protein length: Ser2-Arg593
Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution: Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name: PTPN11 protein tyrosine phosphatase, non-receptor type 11 [ Homo sapiens ]
Official Symbol: PTPN11
Synonyms: PTPN11; protein tyrosine phosphatase, non-receptor type 11; Noonan syndrome 1 , NS1; tyrosine-protein phosphatase non-receptor type 11; BPTP3; PTP2C; SH PTP2; SHP 2; SHP2; PTP-2C; protein tyrosine phosphatase-2; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; CFC; NS1; PTP-1D; SH-PTP2; SH-PTP3; MGC14433;
Gene ID: 5781
mRNA Refseq: NM_002834
Protein Refseq: NP_002825
MIM: 176876
UniProt ID: Q06124
Chromosome Location: 12q24.1

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