Recombinant Human PTPN11 Protein, His-tagged

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Recombinant Human PTPN11 Protein, His-tagged

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Cat.No. : PTPN11-519H
Product Overview : Recombinant Human PTPN11 (Accession # NP_002825) Ser2-Arg593, fused with an N-terminal 6-His tag, was produced in E. coli.
Source : E. coli
Species : Human
Tag : His
Predicted N Terminal : His
Form : Supplied as a 0.2 µm filtered solution in Tris, NaCl, Glycerol and DTT.
Bio-activity : Measured by its ability to dephosphorylate a tyrosine residue in a peptide containing the EGFR Y992 phosphorylation site.The specific activity is >1.2 µmol/min/mg, measured under the described conditions.
Molecular Mass : Recombinant Human PTPN11, His-tagged has a calculated MW of 69 kDa. In SDS-PAGE migrates as 63-70 kDa, reducing conditions.
Protein length : Ser2-Arg593
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 100 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : PTPN11 protein tyrosine phosphatase, non-receptor type 11 [ Homo sapiens ]
Official Symbol : PTPN11
Synonyms : PTPN11; protein tyrosine phosphatase, non-receptor type 11; Noonan syndrome 1 , NS1; tyrosine-protein phosphatase non-receptor type 11; BPTP3; PTP2C; SH PTP2; SHP 2; SHP2; PTP-2C; protein tyrosine phosphatase-2; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; CFC; NS1; PTP-1D; SH-PTP2; SH-PTP3; MGC14433;
Gene ID : 5781
mRNA Refseq : NM_002834
Protein Refseq : NP_002825
MIM : 176876
UniProt ID : Q06124
Chromosome Location : 12q24.1
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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