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Recombinant Human SCGB1A1 protein

Cat.No. : SCGB1A1-533H
Product Overview : Recombinant Human SCGB1A1 protein was expressed in Escherichia coli.
  • Specification
  • Gene Information
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Description : This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.
Source : E.coli
Species : Human
Form : Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4.
Bio-activity : Fully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 μg/ml, corresponding to a specific activity of > 200 IU/mg.
Molecular Mass : Approximately 15.8 kDa, a disulfide-linked homodimeric protein containing two 70 amino acid residues polypeptide.
Protein length : 70
AA Sequence : EICPSFQRVIETLLMDTPSSYEAAM ELFSPDQDMREAGAQLKKLVDTLPQ KPRESIIKLMEKIAQSSLCN
Endotoxin : Less than 0.1 EU/µg of rHuUteroglobin as determined by LAL method.
Purity : >98% by SDS-PAGE and HPLC analysis.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : SCGB1A1
Official Symbol : SCGB1A1
Synonyms : SCGB1A1; secretoglobin, family 1A, member 1 (uteroglobin); UGB, uteroglobin; uteroglobin; CC10; CC16; CCSP; Uteroglobin (Clara cell specific 10 kD protein); blastokinin; urine protein 1; urinary protein 1; clara cells 10 kDa secretory protein; clara cell phospholipid-binding protein; UGB; UP1; UP-1; CCPBP;
Gene ID : 7356
mRNA Refseq : NM_003357
Protein Refseq : NP_003348
MIM : 192020
UniProt ID : P11684

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does SCGB1A1 influence the response of lung tissue to environmental pollutants and allergens? 02/14/2022

SCGB1A1 helps protect lung tissue from environmental pollutants and allergens, reducing the risk of damage and inflammation.

What are the mechanisms by which SCGB1A1 modulates immune cell recruitment and activation in the lungs? 09/04/2021

SCGB1A1 influences immune cell behavior in the lungs, affecting responses to infections and inflammation.

How does SCGB1A1 (Secretoglobin Family 1A Member 1) function in respiratory tract defense and lung homeostasis? 08/15/2020

SCGB1A1 is important for respiratory defense, contributing to the maintenance of lung health and protection against irritants.

What is the impact of SCGB1A1 in asthma and chronic obstructive pulmonary disease (COPD) pathogenesis? 06/15/2020

SCGB1A1 is implicated in the pathogenesis of asthma and COPD, influencing airway inflammation and reactivity.

How do alterations in SCGB1A1 expression or function affect respiratory infections and healing after lung injury? 03/30/2020

Changes in SCGB1A1 expression can impact the body's ability to fight respiratory infections and heal after lung injuries.

What role does SCGB1A1 play in modulating inflammatory responses in chronic lung diseases? 01/01/2019

SCGB1A1 modulates inflammation in chronic lung conditions, potentially impacting disease progression.

How does SCGB1A1 contribute to mucus production and airway protection? 10/13/2018

SCGB1A1 plays a role in mucus production, essential for trapping and clearing pathogens and particles from the airways.

Customer Reviews (3)

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Reviews
02/07/2022

    Precise antibody validation, enhances our immunoprecipitation accuracy.

    06/07/2019

      Efficient protein purification, delivers high yield and purity consistently.

      03/25/2019

        Timely protein expression optimization, greatly boosts our research efforts.

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