"BCL2L11" Related Products

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Recombinant Human BCL2L11 Protein, His-tagged

Cat.No.: BCL2L11-572H
Product Overview: Recombinant Human BCL2L11 (Accession # NP_006529) Ala2-Arg120, fused with an N-terminal 6-His tag, was produced in E. coli.
Source: E. coli
Species: Human
Tag: His
Predicted N Terminal: His
Form: Supplied as a 0.2 µm filtered solution in HEPES-KOH, DTT, KCl and Glycerol.
Bio-activity: Measured by its ability to neutralize anti-apoptotic Bcl-2 family member inhibition of Recombinant Human BID Caspase-8-cleaved-mediated Cytochrome c release from isolated mitochondria. Release of Cytochrome c is quantified using the Rat/Mouse Cytochrome c Quantikine ELISA.The typical EC50 value in this assay is 0.1-2 µM. Optimal dose should be determined for each application.
Molecular Mass: Recombinant Human BCL2L11, His-tagged has a calculated MW of 14.3 kDa. In SDS-PAGE migrates as 16 kDa doublet, under reducing and non-reducing conditions.
Protein length: Ala2-Arg120
Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution: Reconstitute at 50 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name: BCL2L11 BCL2-like 11 (apoptosis facilitator) [ Homo sapiens ]
Official Symbol: BCL2L11
Synonyms: BCL2L11; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; BIM; BimEL; BimL; BOD; bcl2-L-11; bcl-2 interacting protein Bim; bcl-2-related ovarian death agonist; bcl-2 interacting mediator of cell death; BAM; BIM-beta6; BIM-beta7; BIM-alpha6;
Gene ID: 10018
mRNA Refseq: NM_001204106
Protein Refseq: NP_001191035
MIM: 603827
UniProt ID: O43521
Chromosome Location: 2q13

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