Recombinant Human BCL2L11 Protein, His-tagged BCL2L11-572H

Recombinant Human BCL2L11 Protein, His-tagged

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Recombinant Human BCL2L11 Protein, His-tagged

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Cat.No. : BCL2L11-572H
Product Overview : Recombinant Human BCL2L11 (Accession # NP_006529) Ala2-Arg120, fused with an N-terminal 6-His tag, was produced in E. coli.
Source : E. coli
Species : Human
Tag : His
Predicted N Terminal : His
Form : Supplied as a 0.2 µm filtered solution in HEPES-KOH, DTT, KCl and Glycerol.
Bio-activity : Measured by its ability to neutralize anti-apoptotic Bcl-2 family member inhibition of Recombinant Human BID Caspase-8-cleaved-mediated Cytochrome c release from isolated mitochondria. Release of Cytochrome c is quantified using the Rat/Mouse Cytochrome c Quantikine ELISA.The typical EC50 value in this assay is 0.1-2 µM. Optimal dose should be determined for each application.
Molecular Mass : Recombinant Human BCL2L11, His-tagged has a calculated MW of 14.3 kDa. In SDS-PAGE migrates as 16 kDa doublet, under reducing and non-reducing conditions.
Protein length : Ala2-Arg120
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 50 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : BCL2L11 BCL2-like 11 (apoptosis facilitator) [ Homo sapiens ]
Official Symbol : BCL2L11
Synonyms : BCL2L11; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; BIM; BimEL; BimL; BOD; bcl2-L-11; bcl-2 interacting protein Bim; bcl-2-related ovarian death agonist; bcl-2 interacting mediator of cell death; BAM; BIM-beta6; BIM-beta7; BIM-alpha6;
Gene ID : 10018
mRNA Refseq : NM_001204106
Protein Refseq : NP_001191035
MIM : 603827
UniProt ID : O43521
Chromosome Location : 2q13

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