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Recombinant Human NRG1

Cat.No.: NRG1-678H
Product Overview: Recombinant Human NRG1 (Accession # NP_039250) Thr176-Lys246, fused with , was produced in E. coli.
Source: E. coli
Species: Human
Predicted N Terminal: Thr176
Form: Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Bio-activity: Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083.The ED50 for this effect is typically 0.06-0.3 ng/mL.
Molecular Mass: Recombinant Human NRG1 has a calculated MW of 8 kDa. In SDS-PAGE migrates as 8 kDa, reducing conditions.
Protein length: Thr176-Lys246
Purity: >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name: NRG1 neuregulin 1 [ Homo sapiens ]
Official Symbol: NRG1
Synonyms: NRG1; neuregulin 1; HGL; pro-neuregulin-1, membrane-bound isoform; GGF; HRG; NDF; MSTP131; pro-NRG1; glial growth factor; neu differentiation factor; neuregulin 1 type IV beta 3; neuregulin 1 type IV beta 1a; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator); ARIA; GGF2; HRG1; HRGA; SMDF; MST131;
Gene ID: 3084
mRNA Refseq: NM_001159995
Protein Refseq: NP_001153467
MIM: 142445
UniProt ID: Q02297
Chromosome Location: 8p21-p12

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