Recombinant Mouse Vsig4 Protein, Fc Chimera


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Recombinant Mouse Vsig4 Protein, Fc Chimera

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Cat.No. : Vsig4-861M
Product Overview : Recombinant Mouse Vsig4 (Accession # NP_808457), fused with , was produced in Mouse myeloma cell line, NS0-derived.
Source : NSO Cells
Species : Mouse
Tag : Fc
Predicted N Terminal : His20
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its ability to inhibit anti-CD3-induced proliferation of splenic T lymphocytes. Vogt, L. et al. (2006) J. Clin. Invest. 116:2817.The presence of immobilized rmVSIG4/Fc Chimera inhibited the anti-CD3 response by 50% - 70%. The ED50 for this effect is typically 1.25 - 5 µg/mL.Measured by its ability to bind human iC3b in a functional ELISA. Optimal dilutions should be determined by each laboratory for each application.
Molecular Mass : Recombinant Mouse Vsig4, Fc Chimera has a calculated MW of 46 kDa (monomer). In SDS-PAGE migrates as 60-65 kDa, reducing conditions.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : Vsig4 V-set and immunoglobulin domain containing 4 [ Mus musculus ]
Official Symbol : Vsig4
Synonyms : VSIG4; V-set and immunoglobulin domain containing 4; V-set and immunoglobulin domain-containing protein 4; complement receptor of the immunoglobulin superfamily; CRIg; Z39IG; BC025105; A530061A11; MGC36211;
Gene ID : 278180
mRNA Refseq : NM_177789
Protein Refseq : NP_808457
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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