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Active Recombinant Human SIGLEC6 Protein, Fc Chimera

Cat.No. : SIGLEC6-876H
Product Overview : Recombinant Human SIGLEC6 (Accession # NP_942142), fused with , was produced in Chinese Hamster Ovary cell line, CHO-derived.
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Source : CHO Cells
Species : Human
Tag : Fc
Predicted N Terminal : No results obtained: Gln27 predicted
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its ability to bind biotinylated Neu5Ac alpha 2-6GalNAc alpha (sialyl-Tn). Patel, N. et al. (1999) The Journal of Biological Chemistry 274:22729.
Molecular Mass : Recombinant Human SIGLEC6, Fc Chimera has a calculated MW of 60.3 kDa (monomer). In SDS-PAGE migrates as 80-95 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : SIGLEC6 sialic acid binding Ig-like lectin 6 [ Homo sapiens ]
Official Symbol : SIGLEC6
Synonyms : SIGLEC6; sialic acid binding Ig-like lectin 6; CD33L, CD33L1; sialic acid-binding Ig-like lectin 6; CD327; OB BP1; SIGLEC 6; CD33 antigen-like 1; obesity-binding protein 1; CD33L; OBBP1; CD33L1; CD33L2; CDW327;
Gene ID : 946
mRNA Refseq : NM_001177547
Protein Refseq : NP_001171018
MIM : 604405
UniProt ID : O43699
Chromosome Location : 19q13.3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What are the future prospects for the clinical application of SIGLEC6 protein? 08/16/2021

The clinical application of SIGLEC6 protein holds promise for advancing the diagnosis, treatment, and monitoring of autoimmune diseases, inflammatory conditions, and cancer, with ongoing research paving the way for potential therapeutic interventions.

Are there any genetic variations in SIGLEC6 protein associated with disease susceptibility? 04/02/2021

Genetic variations in the SIGLEC6 gene have been investigated for their potential association with disease susceptibility, particularly in autoimmune and inflammatory conditions.

How does SIGLEC6 protein interact with other immune receptors? 08/29/2018

SIGLEC6 protein has been shown to interact with other immune receptors, potentially influencing the overall immune response and its contribution to disease pathology.

Can SIGLEC6 protein be targeted for drug development? 06/27/2017

Given its involvement in immune regulation and inflammatory processes, SIGLEC6 protein is a potential target for drug development in the treatment of autoimmune and inflammatory diseases.

Can SIGLEC6 protein be used as a therapeutic target in immunotherapy? 05/17/2016

The potential use of SIGLEC6 protein as a therapeutic target in immunotherapy is an area of active investigation, particularly in the context of modulating immune responses in cancer treatment.

Customer Reviews (3)

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10/28/2022

    Their expertise and prompt assistance can effectively address any concerns or challenges that may arise during the experimental process.

    06/30/2022

      In addition to its outstanding quality, the manufacturer of the SIGLEC6 protein provides excellent technical support, which is a valuable asset for researchers

      10/24/2016

        The SIGLEC6 protein is of exceptional quality, making it an ideal choice to meet my experimental requirements.

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