Active Recombinant Human SIGLEC6 Protein, Fc Chimera
Cat.No. : | SIGLEC6-876H |
Product Overview : | Recombinant Human SIGLEC6 (Accession # NP_942142), fused with , was produced in Chinese Hamster Ovary cell line, CHO-derived. |
- Specification
- Gene Information
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Source : | CHO Cells |
Species : | Human |
Tag : | Fc |
Predicted N Terminal : | No results obtained: Gln27 predicted |
Form : | Lyophilized from a 0.2 µm filtered solution in PBS. |
Bio-activity : | Measured by its ability to bind biotinylated Neu5Ac alpha 2-6GalNAc alpha (sialyl-Tn). Patel, N. et al. (1999) The Journal of Biological Chemistry 274:22729. |
Molecular Mass : | Recombinant Human SIGLEC6, Fc Chimera has a calculated MW of 60.3 kDa (monomer). In SDS-PAGE migrates as 80-95 kDa, reducing conditions. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name : | SIGLEC6 sialic acid binding Ig-like lectin 6 [ Homo sapiens ] |
Official Symbol : | SIGLEC6 |
Synonyms : | SIGLEC6; sialic acid binding Ig-like lectin 6; CD33L, CD33L1; sialic acid-binding Ig-like lectin 6; CD327; OB BP1; SIGLEC 6; CD33 antigen-like 1; obesity-binding protein 1; CD33L; OBBP1; CD33L1; CD33L2; CDW327; |
Gene ID : | 946 |
mRNA Refseq : | NM_001177547 |
Protein Refseq : | NP_001171018 |
MIM : | 604405 |
UniProt ID : | O43699 |
Chromosome Location : | 19q13.3 |
Products Types
◆ Recombinant Protein | ||
SIGLEC6-446H | Recombinant Human SIGLEC6 Protein, Fc-tagged | +Inquiry |
SIGLEC6-191H | Recombinant Human SIGLEC6 Protein, His-tagged | +Inquiry |
SIGLEC6-55H | Recombinant Human SIGLEC6 Protein, Fc-His-tagged | +Inquiry |
SIGLEC6-1086H | Recombinant Human SIGLEC6 protein(Gln27-Val331), His-tagged | +Inquiry |
SIGLEC6-13H | Recombinant Human SIGLEC6 Protein (27-347), C-Fc-Avi tagged | +Inquiry |
◆ Lysates | ||
SIGLEC6-795HCL | Recombinant Human SIGLEC6 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThe clinical application of SIGLEC6 protein holds promise for advancing the diagnosis, treatment, and monitoring of autoimmune diseases, inflammatory conditions, and cancer, with ongoing research paving the way for potential therapeutic interventions.
Genetic variations in the SIGLEC6 gene have been investigated for their potential association with disease susceptibility, particularly in autoimmune and inflammatory conditions.
SIGLEC6 protein has been shown to interact with other immune receptors, potentially influencing the overall immune response and its contribution to disease pathology.
Given its involvement in immune regulation and inflammatory processes, SIGLEC6 protein is a potential target for drug development in the treatment of autoimmune and inflammatory diseases.
The potential use of SIGLEC6 protein as a therapeutic target in immunotherapy is an area of active investigation, particularly in the context of modulating immune responses in cancer treatment.
Customer Reviews (3)
Write a reviewTheir expertise and prompt assistance can effectively address any concerns or challenges that may arise during the experimental process.
In addition to its outstanding quality, the manufacturer of the SIGLEC6 protein provides excellent technical support, which is a valuable asset for researchers
The SIGLEC6 protein is of exceptional quality, making it an ideal choice to meet my experimental requirements.
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