Active Recombinant Mouse Cx3cl1 Protein, His-tagged
Cat.No. : | Cx3cl1-951M |
Product Overview : | Recombinant Mouse Cx3cl1 (Accession # O35188) Gln25-Arg337, fused with a C-terminal 6-His tag, was produced in Spodoptera frugiperda, Sf 21 (baculovirus)-derived. |
- Specification
- Gene Information
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Source : | Baculovirus Sf21 Insect Cells |
Species : | Mouse |
Tag : | His |
Predicted N Terminal : | No results obtained: Gln25 predicted |
Form : | Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein. |
Bio-activity : | Measured by its ability to chemoattract freshly isolated human peripheral blood lymphocytes (PBL).The ED50 for this effect is typically 0.2 - 0.6 µg/mL.Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CX3CR1.The ED50 for this effect is typically 0.03 - 0.12 µg/mL. |
Molecular Mass : | Recombinant Mouse Cx3cl1, His-tagged has a calculated MW of 34 kDa. In SDS-PAGE migrates as 90 kDa, reducing conditions. |
Protein length : | Gln25-Arg337 |
Purity : | >97%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name : | Cx3cl1 chemokine (C-X3-C motif) ligand 1 [ Mus musculus ] |
Official Symbol : | Cx3cl1 |
Synonyms : | CX3CL1; chemokine (C-X3-C motif) ligand 1; fractalkine; neurotactin; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D, 1; CX3C; Cxc3; Scyd1; ABCD-3; AB030188; AI848747; D8Bwg0439e; |
Gene ID : | 20312 |
mRNA Refseq : | NM_009142 |
Protein Refseq : | NP_033168 |
MIM : |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCX3CL1 is involved in pain modulation, and its dysregulation is associated with neuropathic pain conditions. Understanding its role may lead to the development of novel analgesic therapies.
Yes, several clinical trials are investigating the therapeutic potential of targeting CX3CL1 in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.
CX3CL1 contributes to inflammation in cardiovascular diseases and affects vascular function. Studying its role helps in understanding the pathophysiology of conditions like atherosclerosis.
CX3CL1 acts as a chemoattractant, facilitating the recruitment and activation of immune cells at the site of inflammation, playing a pivotal role in immune response regulation.
Researchers are exploring CX3CL1 as a potential biomarker for diseases such as rheumatoid arthritis and certain cancers, aiming to develop diagnostic tools and monitor disease progression.
Customer Reviews (3)
Write a reviewthe CX3CL1 protein's compatibility with various experimental techniques further supports its usability.
One of the standout features of the CX3CL1 protein is the excellent technical support provided by the manufacturer.
Whether I need to study protein-protein interactions, protein localization, or protein folding, the CX3CL1 protein consistently delivers precise and meaningful data.
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