Active Recombinant Human UNC5C Protein, Fc Chimera

• Cat.No.: UNC5C-1072H
• Product Overview: Recombinant Human UNC5C (Accession # O95185), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Fc
• Predicted N Terminal: Ala40
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.Immobilized rhUNC5H3/Fc Chimera at 5 µg/mL (100 µL/well) can bind rcNetrin-1 with a linear range of 6 - 400 ng/mL.
• Molecular Mass: Recombinant Human UNC5C, Fc Chimera has a calculated MW of 64.6 kDa (monomer). In SDS-PAGE migrates as 90 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 10 µg/mL in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: UNC5C unc-5 homolog C (C. elegans) [ Homo sapiens ]
• Official Symbol: UNC5C
• Synonyms: UNC5C; unc-5 homolog C (C. elegans); unc5 (C.elegans homolog) c; netrin receptor UNC5C; unc-5 homolog 3; protein unc-5 homolog 3; protein unc-5 homolog C; UNC5H3
• Gene ID: 8633
• mRNA Refseq: NM_003728
• Protein Refseq: NP_003719
• MIM: 603610
• UniProt ID: O95185
• Chromosome Location: 4q21-q23