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Active Recombinant Rat Gdf11 protein

Cat.No. : Gdf11-1080R
Product Overview : Recombinant Rat Gdf11(Asn299-Ser407) was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Rat
Predicted N Terminal : Met
Form : Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Bio-activity : Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340. The ED50 for this effect is typically 0.8-4.8 ng/mL.
Molecular Mass : Predicted Molecular Mass12.6 (monomer) kDa
Protein length : Asn299-Ser407
Endotoxin : <0.01 eu per 1 μg of the protein by the lal>
Purity : >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : Reconstitute at 100 μg/mL in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.
Shipping : The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Gene Name : Gdf11 growth differentiation factor 11 [ Rattus norvegicus ]
Official Symbol : Gdf11
Synonyms : GDF11; growth differentiation factor 11; growth/differentiation factor 11; GDF-11; bone morphogenetic protein 11; BMP-11;
Gene ID : 29454
mRNA Refseq : NM_017203
Protein Refseq : NP_058899
MIM :
UniProt ID :
Chromosome Location : 7q11
Function : cytokine activity; growth factor activity; molecular_function;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Can GDF11 protein be used to treat some diseases with stem cell therapy? 12/25/2019

The protein can be used to treat some diseases through stem cell therapy, such as using the promoter of GDF11 to activate the self-renewal and regenerative ability of stem cells.

What diseases can GDF11 protein be used as a therapeutic target? 12/13/2019

GDF11 protein can be used as a therapeutic target for a variety of diseases such as muscular dystrophy, osteoporosis, cardiovascular diseases and neurodegenerative diseases.

What is the role of GDF11 protein on bone growth? 12/10/2019

GDF11 protein inhibits the differentiation of well-developed chondrocytes in bone growth plates into osteoblasts, thereby inhibiting bone growth.

Can GDF11 protein be intervened with drugs? 12/02/2019

The GDF11 protein can be intervened by means of drugs, such as using soluble GDF11 receptors to increase the activity of the GDF11 signaling pathway.

Does GDF11 protein promote muscle growth? 10/10/2019

In young animals, GDF11 promotes muscle growth, but in older adults and mice, its effect is not significant.

Does GDF11 protein drive neuroblast production and growth? 09/29/2019

This protein promotes the production and growth of neuroblasts and also plays an important role in the differentiation and function of neural stem cells.

Customer Reviews (3)

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Reviews
04/19/2022

    The repeatability of GDF11 is very good, which can ensure the reliability of the experimental results, and also facilitate the subsequent research and application.

    05/23/2020

      After using GDF11, my experimental results are more stable and reliable, and also convenient for subsequent data analysis.

      03/09/2020

        The band intensity of GDF11 in Western blot was high, which improved the signal-to-noise ratio of the experiment.

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